RPA PHYSICALLY INTERACTS WITH THE HUMAN DNA GLYCOSYLASE NEIL1 TO REGULATE EXCISION OF OXIDATIVE DNA BASE DAMAGE IN PRIMER-TEMPLATE STRUCTURES

The human DNA glycosylase NEIL1, activated during the S-phase, has been shown to excise oxidized base lesions in single-strand DNA substrates. Furthermore, our previous work demonstrating functional interaction of NEIL1 with PCNA and flap endonuclease 1 (FEN1) suggested its involvement in replicatio...

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Autores principales: Theriot, Corey A., Hegde, Muralidhar L., Hazra, Tapas K., Mitra, Sankar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883689/
https://ncbi.nlm.nih.gov/pubmed/20338831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.02.014
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