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Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair
Accumulation of 8-oxo-7,8-dihydroguanine (8-oxoG) in the DNA results in genetic instability and mutagenesis, and is believed to contribute to carcinogenesis, aging processes and various aging-related diseases. 8-OxoG is removed from the DNA via DNA base excision repair (BER), initiated by 8-oxoguani...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797267/ https://ncbi.nlm.nih.gov/pubmed/23890570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.06.006 |
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