Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

Accumulation of 8-oxo-7,8-dihydroguanine (8-oxoG) in the DNA results in genetic instability and mutagenesis, and is believed to contribute to carcinogenesis, aging processes and various aging-related diseases. 8-OxoG is removed from the DNA via DNA base excision repair (BER), initiated by 8-oxoguani...

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Bibliografiset tiedot
Päätekijät: German, Peter, Szaniszlo, Peter, Hajas, Gyorgy, Radak, Zsolt, Bacsi, Attila, Hazra, Tapas K., Hegde, Muralidhar L., Ba, Xueqing, Boldogh, Istvan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797267/
https://ncbi.nlm.nih.gov/pubmed/23890570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.06.006
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