8-oxoguanine DNA glycosylase1–driven DNA repair --a paradoxical role in lung aging

Age-associated changes in lung structure and function are some of the most important predictors of overall health, cognitive activities and longevity. Common to all aging cells is an increase in oxidatively modified DNA bases, primarily 8-oxo-7,8-dihydroguanine (8-oxoG). It is repaired via DNA base...

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Publicado en:Mech Ageing Dev
Autores principales: German, Peter, Saenz, David, Szaniszlo, Peter, Aguilera-Aguirre, Leopoldo, Pan, Lang, Hegde, Muralidhar L., Bacsi, Attila, Hajas, Gyorgy, Radak, Zsolt, Ba, Xueqing, Mitra, Sankar, Papaconstantinou, John, Boldogh, Istvan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177546/
https://ncbi.nlm.nih.gov/pubmed/27343030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.06.009
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