8-oxoguanine DNA glycosylase1–driven DNA repair --a paradoxical role in lung aging

Age-associated changes in lung structure and function are some of the most important predictors of overall health, cognitive activities and longevity. Common to all aging cells is an increase in oxidatively modified DNA bases, primarily 8-oxo-7,8-dihydroguanine (8-oxoG). It is repaired via DNA base...

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Gepubliceerd in:Mech Ageing Dev
Hoofdauteurs: German, Peter, Saenz, David, Szaniszlo, Peter, Aguilera-Aguirre, Leopoldo, Pan, Lang, Hegde, Muralidhar L., Bacsi, Attila, Hajas, Gyorgy, Radak, Zsolt, Ba, Xueqing, Mitra, Sankar, Papaconstantinou, John, Boldogh, Istvan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177546/
https://ncbi.nlm.nih.gov/pubmed/27343030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.06.009
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