8-oxoguanine DNA glycosylase1–driven DNA repair --a paradoxical role in lung aging

Age-associated changes in lung structure and function are some of the most important predictors of overall health, cognitive activities and longevity. Common to all aging cells is an increase in oxidatively modified DNA bases, primarily 8-oxo-7,8-dihydroguanine (8-oxoG). It is repaired via DNA base...

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Detalhes bibliográficos
Publicado no:Mech Ageing Dev
Main Authors: German, Peter, Saenz, David, Szaniszlo, Peter, Aguilera-Aguirre, Leopoldo, Pan, Lang, Hegde, Muralidhar L., Bacsi, Attila, Hajas, Gyorgy, Radak, Zsolt, Ba, Xueqing, Mitra, Sankar, Papaconstantinou, John, Boldogh, Istvan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177546/
https://ncbi.nlm.nih.gov/pubmed/27343030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.06.009
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