Phospholipids and Alzheimer’s Disease: Alterations, Mechanisms and Potential Biomarkers

著者: Kosicek, Marko, Hecimovic, Silva
出版事項 2013

Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

著者: Kosicek, Marko, Malnar, Martina, Goate, Alison, Hecimovic, Silva
出版事項 2010

Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins

著者: Cermak, Stjepko, Kosicek, Marko, Mladenovic-Djordjevic, Aleksandra, Smiljanic, Kosara, Kanazir, Selma, Hecimovic, Silva
出版年 PLoS One (2016)

N-glycome of the Lysosomal Glycocalyx is Altered in Niemann-Pick Type C Disease (NPC) Model Cells

著者: Kosicek, Marko, Gudelj, Ivan, Horvatic, Anita, Jovic, Tanja, Vuckovic, Frano, Lauc, Gordan, Hecimovic, Silva
出版年 Mol Cell Proteomics (2018)

Niemann Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway

著者: Malnar, Martina, Kosicek, Marko, Mitterreiter, Stefan, Omerbasic, Damir, Lichtenthaler, Stefan F., Goate, Alison, Hecimovic, Silva
出版事項 2010

Characterization of N-Terminal Processing of Group VIA Phospholipase A(2) and of Potential Cleavage Sites of Amyloid Precursor Protein Constructs by Automated Identification of Sig...

著者: Song, Haowei, Hecimovic, Silva, Goate, Alison, Hsu, Fong-Fu, Bao, Shunzhong, Vidavsky, Ilan, Ramanadham, Sasanka, Turk, John
出版事項 2004

Cholesterol-Dependent Energy Transfer between Fluorescent Proteins—Insights into Protein Proximity of APP and BACE1 in Different Membranes in Niemann-Pick Type C Disease Cells

著者: von Einem, Bjoern, Weber, Petra, Wagner, Michael, Malnar, Martina, Kosicek, Marko, Hecimovic, Silva, von Arnim, Christine A. F., Schneckenburger, Herbert
出版事項 2012

Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors

著者: Dražić, Tonko, Sachdev, Vinay, Leopold, Christina, Patankar, Jay V., Malnar, Martina, Hećimović, Silva, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar
出版年 Bioorg Med Chem (2015)

Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors

著者: Dražić, Tonko, Molčanov, Krešimir, Sachdev, Vinay, Malnar, Martina, Hećimović, Silva, Patankar, Jay V., Obrowsky, Sascha, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar
出版年 Eur J Med Chem (2014)

A novel PSEN1 Mutation (I238M) associated with early-onset Alzheimer’s disease in an African-American woman

著者: Ting, Simon Kang Seng, Benzinger, Tammie, Kepe, Vladimir, Fagan, Anne, Coppola, Giovanni, Porter, Verna, Hecimovic, Silva, Chakraverty, Suma, Alvarez-Retuerto, Ana Isabel, Goate, Alison, Ringman, John M.
出版事項 2014

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

著者: Colombo, Alessio, Dinkel, Lina, Müller, Stephan A., Sebastian Monasor, Laura, Schifferer, Martina, Cantuti-Castelvetri, Ludovico, König, Jasmin, Vidatic, Lea, Bremova-Ertl, Tatiana, Lieberman, Andrew P., Hecimovic, Silva, Simons, Mikael, Lichtenthaler, Stefan F., Strupp, Michael, Schneider, Susanne A., Tahirovic, Sabina
出版年 Nat Commun (2021)

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains

著者: Causevic, Mirsada, Dominko, Kristina, Malnar, Martina, Vidatic, Lea, Cermak, Stjepko, Pigoni, Martina, Kuhn, Peer-Hendrik, Colombo, Alessio, Havas, Daniel, Flunkert, Stefanie, McDonald, Jessica, Gunnersen, Jenny M., Hutter-Paier, Birgit, Tahirovic, Sabina, Windisch, Manfred, Krainc, Dimitri, Lichtenthaler, Stefan F., Hecimovic, Silva
出版年 PLoS One (2018)

A presenilin dimer at the core of the γ-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis

著者: Schroeter, Eric H., Ilagan, Ma. Xenia G., Brunkan, Anne L., Hecimovic, Silva, Li, Yue-ming, Xu, Min, Lewis, Huw D., Saxena, Meera T., De Strooper, Bart, Coonrod, Archie, Tomita, Taisuke, Iwatsubo, Takeshi, Moore, Chad L., Goate, Alison, Wolfe, Michael S., Shearman, Mark, Kopan, Raphael
出版事項 2003

Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer’s disease due to a novel PSEN1 mutation

著者: Ringman, John M., Gylys, Karen H., Medina, Luis D., Fox, Michelle, Kepe, Vladimir, Flores, Deborah L., Apostolova, Liana G., Barrio, Jorge R., Small, Gary, Silverman, Daniel H., Siu, Erin, Cederbaum, Stephen, Hecimovic, Silva, Malnar, Martina, Chakraverty, Suma, Goate, Alison M., Bird, Thomas D., Leverenz, James B.
出版事項 2010