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N-glycome of the Lysosomal Glycocalyx is Altered in Niemann-Pick Type C Disease (NPC) Model Cells

Increasing evidence implicates lysosomal dysfunction in the pathogenesis of neurodegenerative diseases, including the rare inherited lysosomal storage disorders (LSDs) and the most common neurodegenerative diseases, such as Alzheimer's and Parkinson's disease (AD and PD). Although the trig...

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Publicat a:Mol Cell Proteomics
Autors principals: Kosicek, Marko, Gudelj, Ivan, Horvatic, Anita, Jovic, Tanja, Vuckovic, Frano, Lauc, Gordan, Hecimovic, Silva
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880104/
https://ncbi.nlm.nih.gov/pubmed/29367433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000129
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