Characterization of N-Terminal Processing of Group VIA Phospholipase A(2) and of Potential Cleavage Sites of Amyloid Precursor Protein Constructs by Automated Identification of Signature Peptides in LC/MS/MS Analyses of Proteolytic Digests

Dysregulation of proteolytic processing of the amyloid precursor protein (APP) contributes to the pathogenesis of Alzheimer’s Disease, and the Group VIA phospholipase A(2) (iPLA(2)β) is the dominant PLA(2) enzyme in the central nervous system and is subject to regulatory proteolytic processing. We h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Song, Haowei, Hecimovic, Silva, Goate, Alison, Hsu, Fong-Fu, Bao, Shunzhong, Vidavsky, Ilan, Ramanadham, Sasanka, Turk, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732747/
https://ncbi.nlm.nih.gov/pubmed/15589755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2004.08.012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados