VH-VL orientation prediction for antibody humanization candidate selection: A case study

Por Bujotzek, Alexander, Lipsmeier, Florian, Harris, Seth F, Benz, Jörg, Kuglstatter, Andreas, Georges, Guy
Publicado no MAbs (2015)

Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration

Por Koenig, Patrick, Lee, Chingwei V., Sanowar, Sarah, Wu, Ping, Stinson, Jeremy, Harris, Seth F., Fuh, Germaine
Publicado no J Biol Chem (2015)

Nanolitre-scale crystallization using acoustic liquid-transfer technology

Por Villaseñor, Armando G., Wong, April, Shao, Ada, Garg, Ankur, Donohue, Timothy J., Kuglstatter, Andreas, Harris, Seth F.
Publicado em 2012

Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

Por Le Pogam, Sophie, Kang, Hyunsoon, Harris, Seth F., Leveque, Vincent, Giannetti, Anthony M., Ali, Samir, Jiang, Wen-Rong, Rajyaguru, Sonal, Tavares, Gisele, Oshiro, Connie, Hendricks, Than, Klumpp, Klaus, Symons, Julian, Browner, Michelle F., Cammack, Nick, Nájera, Isabel
Publicado em 2006

Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus

Por Hang, Julie Qi, Yang, Yanli, Harris, Seth F., Leveque, Vincent, Whittington, Hannah J., Rajyaguru, Sonal, Ao-Ieong, Gloria, McCown, Matthew F., Wong, April, Giannetti, Anthony M., Le Pogam, Sophie, Talamás, Francisco, Cammack, Nick, Nájera, Isabel, Klumpp, Klaus
Publicado em 2009

Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B

Por Schoenfeld, Ryan C., Bourdet, David L., Brameld, Ken A., Chin, Elbert, de Vicente, Javier, Fung, Amy, Harris, Seth F., Lee, Eun K., Pogam, Sophie Le, Leveque, Vincent, Li, Jim, Lui, Alfred S-T., Najera, Isabel, Rajyaguru, Sonal, Sangi, Michael, Steiner, Sandra, Talamas, Francisco X., Taygerly, Joshua P., Zhao, Junping
Publicado em 2013

Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis

Por Ndubaku, Chudi O., Crawford, Terry D., Chen, Huifen, Boggs, Jason W., Drobnick, Joy, Harris, Seth F., Jesudason, Rajiv, McNamara, Erin, Nonomiya, Jim, Sambrone, Amy, Schmidt, Stephen, Smyczek, Tanya, Vitorino, Philip, Wang, Lan, Wu, Ping, Yeung, Stacey, Chen, Jinhua, Chen, Kevin, Ding, Charles Z., Wang, Tao, Xu, Zijin, Gould, Stephen E., Murray, Lesley J., Ye, Weilan
Publicado no ACS Med Chem Lett (2015)

Discovery of N-[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polyme...

Por Talamas, Francisco X., Abbot, Sarah C., Anand, Shalini, Brameld, Ken A., Carter, David S., Chen, Jun, Davis, Dana, de Vicente, Javier, Fung, Amy D., Gong, Leyi, Harris, Seth F., Inbar, Petra, Labadie, Sharada S., Lee, Eun K., Lemoine, Remy, Le Pogam, Sophie, Leveque, Vincent, Li, Jim, McIntosh, Joel, Nájera, Isabel, Park, Jaehyeon, Railkar, Aruna, Rajyaguru, Sonal, Sangi, Michael, Schoenfeld, Ryan C., Staben, Leanna R., Tan, Yunchou, Taygerly, Joshua P., Villaseñor, Armando G., Weller, Paul E.
Publicado em 2013

Outcome of the first wwPDB/CCDC/D3R Ligand Validation Workshop

Por Adams, Paul D., Aertgeerts, Kathleen, Bauer, Cary, Bell, Jeffrey A., Berman, Helen M., Bhat, Talapady N., Blaney, Jeff, Bolton, Evan, Bricogne, Gerard, Brown, David, Burley, Stephen K., Case, David A., Clark, Kirk L., Darden, Tom, Emsley, Paul, Feher, Victoria A., Feng, Zukang, Groom, Colin R., Harris, Seth F., Hendle, Jorg, Holder, Thomas, Joachimiak, Andrzej, Kleywegt, Gerard J., Krojer, Tobias, Marcotrigiano, Joseph, Mark, Alan E., Markley, John L., Miller, Matthew, Minor, Wladek, Montelione, Gaetano T., Murshudov, Garib, Nakagawa, Atsushi, Nakamura, Haruki, Nicholls, Anthony, Nicklaus, Marc, Nolte, Robert T., Padyana, Anil K., Peishoff, Catherine E., Pieniazek, Susan, Read, Randy J., Shao, Chenghua, Sheriff, Steven, Smart, Oliver, Soisson, Stephen, Spurlino, John, Stouch, Terry, Svobodova, Radka, Tempel, Wolfram, Terwilliger, Thomas C., Tronrud, Dale, Velankar, Sameer, Ward, Suzanna, Warren, Gregory L., Westbrook, John D., Williams, Pamela, Yang, Huanwang, Young, Jasmine
Publicado no Structure (2016)