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VH-VL orientation prediction for antibody humanization candidate selection: A case study

Antibody humanization describes the procedure of grafting a non-human antibody's complementarity-determining regions, i.e., the variable loop regions that mediate specific interactions with the antigen, onto a β-sheet framework that is representative of the human variable region germline repert...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:MAbs
Egile Nagusiak: Bujotzek, Alexander, Lipsmeier, Florian, Harris, Seth F, Benz, Jörg, Kuglstatter, Andreas, Georges, Guy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966660/
https://ncbi.nlm.nih.gov/pubmed/26637054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1117720
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