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VH-VL orientation prediction for antibody humanization candidate selection: A case study
Antibody humanization describes the procedure of grafting a non-human antibody's complementarity-determining regions, i.e., the variable loop regions that mediate specific interactions with the antigen, onto a β-sheet framework that is representative of the human variable region germline repert...
Guardat en:
| Publicat a: | MAbs |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966660/ https://ncbi.nlm.nih.gov/pubmed/26637054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1117720 |
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