Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG)

door Harp, Joel M., Coates, Leighton, Sullivan, Brendan, Egli, Martin
Gepubliceerd in Acta Crystallogr F Struct Biol Commun (2018)

Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography

door Harp, Joel M, Coates, Leighton, Sullivan, Brendan, Egli, Martin
Gepubliceerd in Nucleic Acids Res (2021)

Structure of the heterodimeric ecdysone receptor DNA-binding complex

door Devarakonda, Srikripa, Harp, Joel M., Kim, Youngchang, Ożyhar, Andrzej, Rastinejad, Fraydoon
Gepubliceerd in 2003

Expedient placement of two fluorescent dyes for investigating dynamic DNA protein interactions in real time

door Leuba, Sanford H., Anand, Syam P., Harp, Joel M., Khan, Saleem A.
Gepubliceerd in 2008

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2′-deoxyguanosine

door Su, Yan, Patra, Amritraj, Harp, Joel M., Egli, Martin, Guengerich, F. Peter
Gepubliceerd in J Biol Chem (2015)

Computational design of an endo-1,4-β-xylanase ligand binding site

door Morin, Andrew, Kaufmann, Kristian W., Fortenberry, Carie, Harp, Joel M., Mizoue, Laura S., Meiler, Jens
Gepubliceerd in 2011

Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase,

door Wadington, Megan C., Ladner, Jane E., Stourman, Nina V., Harp, Joel M., Armstrong, Richard N.
Gepubliceerd in 2009

Total Synthesis of Stemaphylline N-oxide and Related C9a-Epimeric Analogs

door Schulte, Michael L., Turlington, Mark L., Phatak, Sharangdhar S., Harp, Joel M., Stauffer, Shaun R., Lindsley, Craig W.
Gepubliceerd in 2013

Structure and Function of YghU, A Nu-class Glutathione Transferase Related to YfcG from Escherichia coli,

door Stourman, Nina V., Branch, Megan C., Schaab, Matthew R., Harp, Joel M., Ladner, Jane E., Armstrong, Richard N.
Gepubliceerd in 2011

Molecular Basis for Cyclooxygenase Inhibition by the Non-steroidal Anti-inflammatory Drug Naproxen

door Duggan, Kelsey C., Walters, Matthew J., Musee, Joel, Harp, Joel M., Kiefer, James R., Oates, John A., Marnett, Lawrence J.
Gepubliceerd in 2010

Evaluation of TSPO PET Ligands [(18)F]VUIIS1009A and [(18)F]VUIIS1009B: Tracers for Cancer Imaging

door Tang, Dewei, Li, Jun, Buck, Jason R., Tantawy, Mohamed Noor, Xia, Yan, Harp, Joel M., Nickels, Michael L., Meiler, Jens, Manning, H. Charles
Gepubliceerd in Mol Imaging Biol (2017)

Synthesis and Structure-Activity Relationships of 5,6,7-substituted Pyrazolopyrimidines: Discovery of a novel TSPO PET Ligand for Cancer Imaging

door Tang, Dewei, McKinley, Eliot T., Hight, Matthew R., Uddin, Md. Imam, Harp, Joel M., Fu, Allie, Nickels, Michael L., Buck, Jason R., Manning, H. Charles
Gepubliceerd in 2013

Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections

door Lepesheva, Galina I., Park, Hee-Won, Hargrove, Tatiana Y., Vanhollebeke, Benoit, Wawrzak, Zdzislaw, Harp, Joel M., Sundaramoorthy, Munirathinam, Nes, W. David, Pays, Etienne, Chaudhuri, Minu, Villalta, Fernando, Waterman, Michael R.
Gepubliceerd in 2010

Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity

door Harp, Joel M, Guenther, Dale C, Bisbe, Anna, Perkins, Lydia, Matsuda, Shigeo, Bommineni, Gopal R, Zlatev, Ivan, Foster, Donald J, Taneja, Nate, Charisse, Klaus, Maier, Martin A, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Egli, Martin
Gepubliceerd in Nucleic Acids Res (2018)

Discovery of the first M(5)-selective and CNS penetrant negative allosteric modulator (NAM) of a muscarinic acetylcholine receptor: (S)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-...

door Gentry, Patrick R., Kokubo, Masaya, Bridges, Thomas M., Kett, Nathan R., Harp, Joel M., Cho, Hyekyung P., Smith, Emery, Chase, Peter, Hodder, Peter S., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Wood, Michael R., Lindsley, Craig W.
Gepubliceerd in 2013

Discovery of VU6005649, a CNS Penetrant mGlu(7/8) Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines

door Abe, Masahito, Seto, Mabel, Gogliotti, Rocco G., Loch, Matthew T., Bollinger, Katrina A., Chang, Sichen, Engelberg, Eileen M., Luscombe, Vincent B., Harp, Joel M., Bubser, Michael, Engers, Darren W., Jones, Carrie K., Rodriguez, Alice L., Blobaum, Anna L., Conn, P. Jeffrey, Niswender, Colleen M., Lindsley, Craig W.
Gepubliceerd in ACS Med Chem Lett (2017)

A Novel M(1) PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity

door Rook, Jerri M., Bertron, Jeanette L., Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Moran, Sean P., Maksymetz, James T., Nance, Kellie D., Dickerson, Jonathan W., Remke, Daniel H., Chang, Sichen, Harp, Joel M., Blobaum, Anna L., Niswender, Colleen M., Jones, Carrie K., Stauffer, Shaun R., Conn, P. Jeffrey, Lindsley, Craig W.
Gepubliceerd in ACS Chem Neurosci (2018)