Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG)

著者: Harp, Joel M., Coates, Leighton, Sullivan, Brendan, Egli, Martin
出版年 Acta Crystallogr F Struct Biol Commun (2018)

Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography

著者: Harp, Joel M, Coates, Leighton, Sullivan, Brendan, Egli, Martin
出版年 Nucleic Acids Res (2021)

Structure of the heterodimeric ecdysone receptor DNA-binding complex

著者: Devarakonda, Srikripa, Harp, Joel M., Kim, Youngchang, Ożyhar, Andrzej, Rastinejad, Fraydoon
出版事項 2003

Expedient placement of two fluorescent dyes for investigating dynamic DNA protein interactions in real time

著者: Leuba, Sanford H., Anand, Syam P., Harp, Joel M., Khan, Saleem A.
出版事項 2008

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2′-deoxyguanosine

著者: Su, Yan, Patra, Amritraj, Harp, Joel M., Egli, Martin, Guengerich, F. Peter
出版年 J Biol Chem (2015)

Computational design of an endo-1,4-β-xylanase ligand binding site

著者: Morin, Andrew, Kaufmann, Kristian W., Fortenberry, Carie, Harp, Joel M., Mizoue, Laura S., Meiler, Jens
出版事項 2011

Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase,

著者: Wadington, Megan C., Ladner, Jane E., Stourman, Nina V., Harp, Joel M., Armstrong, Richard N.
出版事項 2009

Total Synthesis of Stemaphylline N-oxide and Related C9a-Epimeric Analogs

著者: Schulte, Michael L., Turlington, Mark L., Phatak, Sharangdhar S., Harp, Joel M., Stauffer, Shaun R., Lindsley, Craig W.
出版事項 2013

Structure and Function of YghU, A Nu-class Glutathione Transferase Related to YfcG from Escherichia coli,

著者: Stourman, Nina V., Branch, Megan C., Schaab, Matthew R., Harp, Joel M., Ladner, Jane E., Armstrong, Richard N.
出版事項 2011

Molecular Basis for Cyclooxygenase Inhibition by the Non-steroidal Anti-inflammatory Drug Naproxen

著者: Duggan, Kelsey C., Walters, Matthew J., Musee, Joel, Harp, Joel M., Kiefer, James R., Oates, John A., Marnett, Lawrence J.
出版事項 2010

Evaluation of TSPO PET Ligands [(18)F]VUIIS1009A and [(18)F]VUIIS1009B: Tracers for Cancer Imaging

著者: Tang, Dewei, Li, Jun, Buck, Jason R., Tantawy, Mohamed Noor, Xia, Yan, Harp, Joel M., Nickels, Michael L., Meiler, Jens, Manning, H. Charles
出版年 Mol Imaging Biol (2017)

Synthesis and Structure-Activity Relationships of 5,6,7-substituted Pyrazolopyrimidines: Discovery of a novel TSPO PET Ligand for Cancer Imaging

著者: Tang, Dewei, McKinley, Eliot T., Hight, Matthew R., Uddin, Md. Imam, Harp, Joel M., Fu, Allie, Nickels, Michael L., Buck, Jason R., Manning, H. Charles
出版事項 2013

Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections

著者: Lepesheva, Galina I., Park, Hee-Won, Hargrove, Tatiana Y., Vanhollebeke, Benoit, Wawrzak, Zdzislaw, Harp, Joel M., Sundaramoorthy, Munirathinam, Nes, W. David, Pays, Etienne, Chaudhuri, Minu, Villalta, Fernando, Waterman, Michael R.
出版事項 2010

Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity

著者: Harp, Joel M, Guenther, Dale C, Bisbe, Anna, Perkins, Lydia, Matsuda, Shigeo, Bommineni, Gopal R, Zlatev, Ivan, Foster, Donald J, Taneja, Nate, Charisse, Klaus, Maier, Martin A, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Egli, Martin
出版年 Nucleic Acids Res (2018)

Discovery of the first M(5)-selective and CNS penetrant negative allosteric modulator (NAM) of a muscarinic acetylcholine receptor: (S)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-...

著者: Gentry, Patrick R., Kokubo, Masaya, Bridges, Thomas M., Kett, Nathan R., Harp, Joel M., Cho, Hyekyung P., Smith, Emery, Chase, Peter, Hodder, Peter S., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Wood, Michael R., Lindsley, Craig W.
出版事項 2013

Discovery of VU6005649, a CNS Penetrant mGlu(7/8) Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines

著者: Abe, Masahito, Seto, Mabel, Gogliotti, Rocco G., Loch, Matthew T., Bollinger, Katrina A., Chang, Sichen, Engelberg, Eileen M., Luscombe, Vincent B., Harp, Joel M., Bubser, Michael, Engers, Darren W., Jones, Carrie K., Rodriguez, Alice L., Blobaum, Anna L., Conn, P. Jeffrey, Niswender, Colleen M., Lindsley, Craig W.
出版年 ACS Med Chem Lett (2017)

A Novel M(1) PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity

著者: Rook, Jerri M., Bertron, Jeanette L., Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Moran, Sean P., Maksymetz, James T., Nance, Kellie D., Dickerson, Jonathan W., Remke, Daniel H., Chang, Sichen, Harp, Joel M., Blobaum, Anna L., Niswender, Colleen M., Jones, Carrie K., Stauffer, Shaun R., Conn, P. Jeffrey, Lindsley, Craig W.
出版年 ACS Chem Neurosci (2018)