Probing the Role of HDACs and Mechanisms of Chromatin-Mediated Neuroplasticity

Bằng Haggarty, Stephen J., Tsai, Li-Huei
Được phát hành 2011

Translation: Screening for Novel Therapeutics Using Disease-Relevant Cell Types Derived from Human Stem Cell Models

Bằng Haggarty, Stephen J., Perlis, Roy H.
Được phát hành 2013

Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies

Bằng Silva, M. Catarina, Haggarty, Stephen J.
Xuất bản năm Int J Mol Sci (2020)

Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: Past, present, and future

Bằng Alural, Begum, Genc, Sermin, Haggarty, Stephen J.
Xuất bản năm Prog Neuropsychopharmacol Biol Psychiatry (2016)

Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch

Bằng Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
Xuất bản năm J Biol Chem (2016)

Toward Development of Epigenetic Drugs for CNS Disorders: Modulating Neuroplasticity via H3K4 Methylation

Bằng Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
Xuất bản năm Psychiatry Clin Neurosci (2016)

SpectralNET – an application for spectral graph analysis and visualization

Bằng Forman, Joshua J, Clemons, Paul A, Schreiber, Stuart L, Haggarty, Stephen J
Được phát hành 2005

Epigenetic Mechanisms in Mood Disorders: Targeting Neuroplasticity

Bằng Fass, Daniel M., Schroeder, Frederick A., Perlis, Roy H., Haggarty, Stephen J.
Được phát hành 2013

Advancing Drug Discovery for Neuropsychiatric Disorders Using Patient-Specific Stem Cell Models

Bằng Haggarty, Stephen J., Silva, M. Catarina, Cross, Alan, Brandon, Nicholas J., Perlis, Roy H.
Xuất bản năm Mol Cell Neurosci (2016)

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

Bằng Haggarty, Stephen J., Koeller, Kathryn M., Wong, Jason C., Grozinger, Christina M., Schreiber, Stuart L.
Được phát hành 2003

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

Bằng Cheng, Chialin, Fass, Daniel M., Folz-Donahue, Kat, MacDonald, Marcy E., Haggarty, Stephen J.
Xuất bản năm Curr Protoc Hum Genet (2017)

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells

Bằng Iaconelli, Jonathan, Lalonde, Jasmin, Watmuff, Bradley, Liu, Bangyan, Mazitschek, Ralph, Haggarty, Stephen J., Karmacharya, Rakesh
Xuất bản năm ACS Chem Biol (2017)

Chemical Genetics Identifies Small-Molecule Modulators of Neuritogenesis Involving Neuregulin-1/ErbB4 Signaling

Bằng Kuai, Letian, Wang, Xiang, Madison, Jon M., Schreiber, Stuart L., Scolnick, Edward M., Haggarty, Stephen J.
Được phát hành 2010

Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration

Bằng Samara, Chrysanthi, Rohde, Christopher B., Gilleland, Cody L., Norton, Stephanie, Haggarty, Stephen J., Yanik, Mehmet Fatih
Được phát hành 2010

Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

Bằng Moreno-Yruela, Carlos, Fass, Daniel M., Cheng, Chialin, Herz, Joachim, Olsen, Christian A., Haggarty, Stephen J.
Xuất bản năm ACS Chem Neurosci (2019)

A High-Throughput Screen for Wnt/β-catenin Signaling Pathway Modulators in Human iPSC-derived Neural Progenitors

Bằng Zhao, Wen-Ning, Cheng, Chialin, Theriault, Kraig M., Sheridan, Steven D., Tsai, Li-Huei, Haggarty, Stephen J.
Được phát hành 2012

Chemical Phylogenetics of Histone Deacetylases

Bằng Bradner, James E., West, Nathan, Grachan, Melissa L., Greenberg, Edward F., Haggarty, Stephen J., Warnow, Tandy, Mazitschek, Ralph
Được phát hành 2010

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

Bằng Huang, Jing, Zhu, Heng, Haggarty, Stephen J., Spring, David R., Hwang, Heejun, Jin, Fulai, Snyder, Michael, Schreiber, Stuart L.
Được phát hành 2004

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

Bằng Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin
Được phát hành 2010

β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome

Bằng Mellios, Nikolaos, Woodson, Jonathan, Garcia, Rodrigo I., Crawford, Benjamin, Sharma, Jitendra, Sheridan, Steven D., Haggarty, Stephen J., Sur, Mriganka
Được phát hành 2014