Chemical Genetics Identifies Small-Molecule Modulators of Neuritogenesis Involving Neuregulin-1/ErbB4 Signaling

[Image: see text] Genetic findings have suggested that neuregulin-1 (Nrg1) and its receptor v-erb-a erythroblastic leukemia viral oncogene homologue 4 (ErbB4) may play a role in neuropsychiatric diseases. However, the downstream signaling events and relevant phenotypic consequences of altered Nrg1 s...

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Main Authors: Kuai, Letian, Wang, Xiang, Madison, Jon M., Schreiber, Stuart L., Scolnick, Edward M., Haggarty, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2010
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873204/
https://ncbi.nlm.nih.gov/pubmed/20495671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn900046a
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