Inter-conversion of Neuregulin2 full and partial agonists for ErbB4

The EGF family hormone NRG2β potently stimulates ErbB4 tyrosine phosphorylation and coupling to IL3 independence. In contrast, the NRG2α splicing isoform has lower affinity for ErbB4, does not potently stimulate ErbB4 phosphorylation, and fails to stimulate ErbB4 coupling. Here we investigate these...

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Detaylı Bibliyografya
Asıl Yazarlar: Wilson, Kristy J., Mill, Christopher P., Cameron, Elizabeth M., Hobbs, Stuart S., Hammer, Robert P., Riese, David J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094732/
https://ncbi.nlm.nih.gov/pubmed/17945187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.10.004
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