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Inter-conversion of Neuregulin2 full and partial agonists for ErbB4

The EGF family hormone NRG2β potently stimulates ErbB4 tyrosine phosphorylation and coupling to IL3 independence. In contrast, the NRG2α splicing isoform has lower affinity for ErbB4, does not potently stimulate ErbB4 phosphorylation, and fails to stimulate ErbB4 coupling. Here we investigate these...

詳細記述

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書誌詳細
主要な著者: Wilson, Kristy J., Mill, Christopher P., Cameron, Elizabeth M., Hobbs, Stuart S., Hammer, Robert P., Riese, David J.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094732/
https://ncbi.nlm.nih.gov/pubmed/17945187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.10.004
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