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The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist
The ErbB4 receptor tyrosine kinase possesses both tumour suppressor and oncogenic activities. Thus pharmacological agents are needed to help elucidate ErbB4 functions. However, limitations of existing ErbB4 agonists and antagonists have led us to seek novel ErbB4 antagonists. The Q43L mutant of the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3960720/ https://ncbi.nlm.nih.gov/pubmed/22216880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110921 |
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