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Toward Development of Epigenetic Drugs for CNS Disorders: Modulating Neuroplasticity via H3K4 Methylation

The mammalian brain dynamically activates or silences gene programs in response to environmental input and developmental cues. This neuroplasticity is controlled by signaling pathways that modify the activity, localization, and/or expression of transcriptional-regulatory enzymes in combination with...

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Detalhes bibliográficos
Publicado no:Psychiatry Clin Neurosci
Main Authors: Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764164/
https://ncbi.nlm.nih.gov/pubmed/27485392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcn.12426
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