Probing the Role of HDACs and Mechanisms of Chromatin-Mediated Neuroplasticity

par Haggarty, Stephen J., Tsai, Li-Huei
Publié 2011

Translation: Screening for Novel Therapeutics Using Disease-Relevant Cell Types Derived from Human Stem Cell Models

par Haggarty, Stephen J., Perlis, Roy H.
Publié 2013

Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies

par Silva, M. Catarina, Haggarty, Stephen J.
Publié dans Int J Mol Sci (2020)

Human Pluripotent Stem Cell-Derived Models and Drug Screening in CNS Precision Medicine

par Silva, M. Catarina, Haggarty, Stephen J.
Publié dans Ann N Y Acad Sci (2019)

Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: Past, present, and future

par Alural, Begum, Genc, Sermin, Haggarty, Stephen J.
Publié dans Prog Neuropsychopharmacol Biol Psychiatry (2016)

Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch

par Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
Publié dans J Biol Chem (2016)

Toward Development of Epigenetic Drugs for CNS Disorders: Modulating Neuroplasticity via H3K4 Methylation

par Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
Publié dans Psychiatry Clin Neurosci (2016)

SpectralNET – an application for spectral graph analysis and visualization

par Forman, Joshua J, Clemons, Paul A, Schreiber, Stuart L, Haggarty, Stephen J
Publié 2005

Epigenetic Mechanisms in Mood Disorders: Targeting Neuroplasticity

par Fass, Daniel M., Schroeder, Frederick A., Perlis, Roy H., Haggarty, Stephen J.
Publié 2013

Advancing Drug Discovery for Neuropsychiatric Disorders Using Patient-Specific Stem Cell Models

par Haggarty, Stephen J., Silva, M. Catarina, Cross, Alan, Brandon, Nicholas J., Perlis, Roy H.
Publié dans Mol Cell Neurosci (2016)

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

par Haggarty, Stephen J., Koeller, Kathryn M., Wong, Jason C., Grozinger, Christina M., Schreiber, Stuart L.
Publié 2003

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

par Cheng, Chialin, Fass, Daniel M., Folz-Donahue, Kat, MacDonald, Marcy E., Haggarty, Stephen J.
Publié dans Curr Protoc Hum Genet (2017)

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells

par Iaconelli, Jonathan, Lalonde, Jasmin, Watmuff, Bradley, Liu, Bangyan, Mazitschek, Ralph, Haggarty, Stephen J., Karmacharya, Rakesh
Publié dans ACS Chem Biol (2017)

Chemical Genetics Identifies Small-Molecule Modulators of Neuritogenesis Involving Neuregulin-1/ErbB4 Signaling

par Kuai, Letian, Wang, Xiang, Madison, Jon M., Schreiber, Stuart L., Scolnick, Edward M., Haggarty, Stephen J.
Publié 2010

Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration

par Samara, Chrysanthi, Rohde, Christopher B., Gilleland, Cody L., Norton, Stephanie, Haggarty, Stephen J., Yanik, Mehmet Fatih
Publié 2010

Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

par Moreno-Yruela, Carlos, Fass, Daniel M., Cheng, Chialin, Herz, Joachim, Olsen, Christian A., Haggarty, Stephen J.
Publié dans ACS Chem Neurosci (2019)

A High-Throughput Screen for Wnt/β-catenin Signaling Pathway Modulators in Human iPSC-derived Neural Progenitors

par Zhao, Wen-Ning, Cheng, Chialin, Theriault, Kraig M., Sheridan, Steven D., Tsai, Li-Huei, Haggarty, Stephen J.
Publié 2012

Chemical Phylogenetics of Histone Deacetylases

par Bradner, James E., West, Nathan, Grachan, Melissa L., Greenberg, Edward F., Haggarty, Stephen J., Warnow, Tandy, Mazitschek, Ralph
Publié 2010

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

par Huang, Jing, Zhu, Heng, Haggarty, Stephen J., Spring, David R., Hwang, Heejun, Jin, Fulai, Snyder, Michael, Schreiber, Stuart L.
Publié 2004

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

par Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin
Publié 2010