Deficits in Adult Neurogenesis, Contextual Fear Conditioning, and Spatial Learning in a Gfap Mutant Mouse Model of Alexander Disease

Autor Hagemann, Tracy L., Paylor, Richard, Messing, Albee
Vydáno 2013

Genetic Ablation of Nrf2/Antioxidant Response Pathway in Alexander Disease Mice Reduces Hippocampal Gliosis but Does Not Impact Survival

Autor Hagemann, Tracy L., Jobe, Emily M., Messing, Albee
Vydáno 2012

GFAP expression as an indicator of disease severity in mouse models of Alexander disease

Autor Jany, Paige L., Hagemann, Tracy L., Messing, Albee
Vydáno 2013

Alexander Disease-Associated Glial Fibrillary Acidic Protein Mutations in Mice Induce Rosenthal Fiber Formation and a White Matter Stress Response

Autor Hagemann, Tracy L., Connor, Jolien X., Messing, Albee
Vydáno v J Neurosci (2006)

Strategies for treatment in Alexander disease

Autor Messing, Albee, Daniels, Christine M. LaPash, Hagemann, Tracy L.
Vydáno 2010

An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease

Autor Wang, Liqun, Hagemann, Tracy L., Messing, Albee, Feany, Mel B.
Vydáno v J Neurosci (2016)

Suppression of GFAP toxicity by αB-crystallin in mouse models of Alexander disease

Autor Hagemann, Tracy L., Boelens, Wilbert C., Wawrousek, Eric F., Messing, Albee
Vydáno 2009

The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment

Autor Toops, Kimberly A, Hagemann, Tracy L, Messing, Albee, Nickells, Robert W
Vydáno 2012

Dual transgenic reporter mice as a tool for monitoring expression of GFAP

Autor Cho, Woosung, Hagemann, Tracy L., Johnson, Delinda A., Johnson, Jeffrey A., Messing, Albee
Vydáno 2009

Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation

Autor Chen, Mei-Hsuan, Hagemann, Tracy L., Quinlan, Roy A., Messing, Albee, Perng, Ming-Der
Vydáno 2013

Nitric oxide mediates glial-induced neurodegeneration in Alexander disease

Autor Wang, Liqun, Hagemann, Tracy L., Kalwa, Hermann, Michel, Thomas, Messing, Albee, Feany, Mel B.
Vydáno v Nat Commun (2015)

Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phen...

Autor Boyd, Michelle M., Litscher, Suzanne J., Seitz, Laura L., Messing, Albee, Hagemann, Tracy L., Collier, Lara S.
Vydáno v J Neuroinflammation (2021)

Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease

Autor Hagemann, Tracy L., Powers, Berit, Mazur, Curt, Kim, Aneeza, Wheeler, Steven, Hung, Gene, Swayze, Eric, Messing, Albee
Vydáno v Ann Neurol (2018)

Alexander Disease Mutant Glial Fibrillary Acidic Protein Compromises Glutamate Transport in Astrocytes

Autor Tian, Rujin, Wu, Xiaoping, Hagemann, Tracy L., Sosunov, Alexandre A., Messing, Albee, McKhann, Guy M., Goldman, James E.
Vydáno 2010

Beneficial Effects of Nrf2 Overexpression in a Mouse Model of Alexander Disease

Autor LaPash Daniels, Christine M., Austin, Elizabeth V., Rockney, Danica E., Jacka, Elizabeth M., Hagemann, Tracy L., Johnson, Delinda A., Johnson, Jeffrey A., Messing, Albee
Vydáno 2012

Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

Autor Wang, Liqun, Xia, Jing, Li, Jonathan, Hagemann, Tracy L., Jones, Jeffrey R., Fraenkel, Ernest, Weitz, David A., Zhang, Su-Chun, Messing, Albee, Feany, Mel B.
Vydáno v Nat Commun (2018)

Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform.

Autor Helman, Guy, Takanohashi, Asako, Hagemann, Tracy L., Perng, Ming D., Walkiewicz, Marzena, Woidill, Sarah, Sase, Sunetra, Cross, Zachary, Du, Yangzhu, Zhao, Ling, Waldman, Amy, Haake, Bret C., Fatemi, Ali, Brenner, Michael, Sherbini, Omar, Messing, Albee, Vanderver, Adeline, Simons, Cas
Vydáno v Hum Mutat (2020)