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Suppression of GFAP toxicity by αB-crystallin in mouse models of Alexander disease
Alexander disease (AxD) is a primary disorder of astrocytes caused by dominant mutations in the gene for glial fibrillary acidic protein (GFAP). These mutations lead to protein aggregation and formation of Rosenthal fibers, complex astrocytic inclusions that contain GFAP, vimentin, plectin, ubiquiti...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655774/ https://ncbi.nlm.nih.gov/pubmed/19129171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp013 |
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