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Nitric oxide mediates glial-induced neurodegeneration in Alexander disease

Glia play critical roles in maintaining the structure and function of the nervous system; however, the specific contribution that astroglia make to neurodegeneration in human disease states remains largely undefined. Here we use Alexander disease, a serious degenerative neurological disorder caused...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Liqun, Hagemann, Tracy L., Kalwa, Hermann, Michel, Thomas, Messing, Albee, Feany, Mel B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674772/
https://ncbi.nlm.nih.gov/pubmed/26608817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9966
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