Beneficial Effects of Nrf2 Overexpression in a Mouse Model of Alexander Disease

Alexander disease is a fatal neurodegenerative disease caused by dominant mutations in glial fibrillary acidic protein (GFAP). The disease is characterized by protein inclusions called Rosenthal fibers within astrocyte cell bodies and processes, and an antioxidant response mediated by the transcript...

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Main Authors: LaPash Daniels, Christine M., Austin, Elizabeth V., Rockney, Danica E., Jacka, Elizabeth M., Hagemann, Tracy L., Johnson, Delinda A., Johnson, Jeffrey A., Messing, Albee
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448488/
https://ncbi.nlm.nih.gov/pubmed/22855800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1494-12.2012
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