Astrocytic TDP-43 Pathology in Alexander Disease

Alexander disease (AxD) is a rare neurodegenerative disorder characterized pathologically by the presence of eosinophilic inclusions known as Rosenthal fibers (RFs) within astrocytes, and is caused by dominant mutations in the coding region of the gene encoding glial fibrillary acidic protein (GFAP)...

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Détails bibliographiques
Auteurs principaux: Walker, Adam K., Daniels, Christine M. LaPash, Goldman, James E., Trojanowski, John Q., Lee, Virginia M.-Y., Messing, Albee
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012304/
https://ncbi.nlm.nih.gov/pubmed/24806671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0248-14.2014
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