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Astrocytic TDP-43 Pathology in Alexander Disease

Alexander disease (AxD) is a rare neurodegenerative disorder characterized pathologically by the presence of eosinophilic inclusions known as Rosenthal fibers (RFs) within astrocytes, and is caused by dominant mutations in the coding region of the gene encoding glial fibrillary acidic protein (GFAP)...

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Autors principals: Walker, Adam K., Daniels, Christine M. LaPash, Goldman, James E., Trojanowski, John Q., Lee, Virginia M.-Y., Messing, Albee
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012304/
https://ncbi.nlm.nih.gov/pubmed/24806671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0248-14.2014
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