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Astrocytic TDP-43 Pathology in Alexander Disease
Alexander disease (AxD) is a rare neurodegenerative disorder characterized pathologically by the presence of eosinophilic inclusions known as Rosenthal fibers (RFs) within astrocytes, and is caused by dominant mutations in the coding region of the gene encoding glial fibrillary acidic protein (GFAP)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012304/ https://ncbi.nlm.nih.gov/pubmed/24806671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0248-14.2014 |
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