Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins

The RNA/DNA-binding protein, TDP-43, is the key component of ubiquitinated inclusions characteristic of amyotrophic lateral sclerosis (ALS) and the majority of frontotemporal lobar degeneration (FTLD-TDP) referred to collectively as TDP-43 proteinopathies. To further elucidate mechanisms of patholog...

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Detalhes bibliográficos
Main Authors: Kwong, Linda K, Irwin, David J, Walker, Adam K, Xu, Yan, Riddle, Dawn M, Trojanowski, John Q, Lee, Virginia M Y
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023626/
https://ncbi.nlm.nih.gov/pubmed/24690345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-33
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