Astrocytic TDP-43 Pathology in Alexander Disease

Alexander disease (AxD) is a rare neurodegenerative disorder characterized pathologically by the presence of eosinophilic inclusions known as Rosenthal fibers (RFs) within astrocytes, and is caused by dominant mutations in the coding region of the gene encoding glial fibrillary acidic protein (GFAP)...

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Detalhes bibliográficos
Main Authors: Walker, Adam K., Daniels, Christine M. LaPash, Goldman, James E., Trojanowski, John Q., Lee, Virginia M.-Y., Messing, Albee
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012304/
https://ncbi.nlm.nih.gov/pubmed/24806671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0248-14.2014
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