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Beneficial Effects of Nrf2 Overexpression in a Mouse Model of Alexander Disease

Alexander disease is a fatal neurodegenerative disease caused by dominant mutations in glial fibrillary acidic protein (GFAP). The disease is characterized by protein inclusions called Rosenthal fibers within astrocyte cell bodies and processes, and an antioxidant response mediated by the transcript...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: LaPash Daniels, Christine M., Austin, Elizabeth V., Rockney, Danica E., Jacka, Elizabeth M., Hagemann, Tracy L., Johnson, Delinda A., Johnson, Jeffrey A., Messing, Albee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448488/
https://ncbi.nlm.nih.gov/pubmed/22855800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1494-12.2012
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