Generating mouse models for biomedical research: technological advances

di Gurumurthy, Channabasavaiah B., Lloyd, Kevin C. Kent
Pubblicato in Dis Model Mech (2019)

Designing and generating a mouse model: frequently asked questions

di Gurumurthy, Channabasavaiah B., Saunders, Thomas L., Ohtsuka, Masato
Pubblicato in J Biomed Res (2021)

Nucleic acids delivery methods for genome editing in zygotes and embryos: the old, the new, and the old-new

di Sato, Masahiro, Ohtsuka, Masato, Watanabe, Satoshi, Gurumurthy, Channabasavaiah B.
Pubblicato in Biol Direct (2016)

Simple and Reliable Genotyping Protocol for Mouse Prkdc(SCID) Mutation

di Quadros, Rolen M., Poluektova, Larisa Y., Gurumurthy, Channabasavaiah B.
Pubblicato in J Immunol Methods (2016)

Easi-CRISPR protocol for creating knock-in and conditional knockout mouse models using long ssDNA donors

di Miura, Hiromi, Quadros, Rolen M., Gurumurthy, Channabasavaiah B., Ohtsuka, Masato
Pubblicato in Nat Protoc (2017)

Insertion of sequences at the original provirus integration site of mouse ROSA26 locus using the CRISPR/Cas9 system

di Quadros, Rolen M., Harms, Donald W., Ohtsuka, Masato, Gurumurthy, Channabasavaiah B.
Pubblicato in FEBS Open Bio (2015)

CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA

di Miura, Hiromi, Gurumurthy, Channabasavaiah B, Sato, Takehito, Sato, Masahiro, Ohtsuka, Masato
Pubblicato in Sci Rep (2015)

Pronuclear Injection-based Targeted Transgenesis

di Schilit, Samantha L.P., Ohtsuka, Masato, Quadros, Rolen, Gurumurthy, Channabasavaiah B.
Pubblicato in Curr Protoc Hum Genet (2016)

Subcellular Localization of Sterol Biosynthesis Enzymes

di Koczok, Katalin, Gurumurthy, Channabasavaiah B., Balogh, István, Korade, Zeljka, Mirnics, Károly
Pubblicato in J Mol Histol (2018)

GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice

di Takahashi, Gou, Gurumurthy, Channabasavaiah B, Wada, Kenta, Miura, Hiromi, Sato, Masahiro, Ohtsuka, Masato
Pubblicato in Sci Rep (2015)

GONAD: a novel CRISPR/Cas9 genome editing method that does not require ex vivo handling of embryos

di Gurumurthy, Channabasavaiah B., Takahashi, Gou, Wada, Kenta, Miura, Hiromi, Sato, Masahiro, Ohtsuka, Masato
Pubblicato in Curr Protoc Hum Genet (2016)

Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

di Nakajima, Kazuhiro, Zhou, Yue, Tomita, Akiko, Hirade, Yoshihiro, Gurumurthy, Channabasavaiah B., Nakada, Shinichiro
Pubblicato in Genome Res (2018)

A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues

di Desaulniers, Amy T., Cederberg, Rebecca A., Carreiro, Elizabeth P., Gurumurthy, Channabasavaiah B., White, Brett R.
Pubblicato in J Biomed Res (2021)

Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model

di Tarang, Shikha, Doi, Songila M. S. R., Gurumurthy, Channabasavaiah B., Harms, Donald, Quadros, Rolen, Rocha-Sanchez, Sonia M.
Pubblicato in Front Cell Neurosci (2015)

Mouse Genome Editing using CRISPR/Cas System

di Harms, Donald W, Quadros, Rolen M, Seruggia, Davide, Ohtsuka, Masato, Takahashi, Gou, Montoliu, Lluis, Gurumurthy, Channabasavaiah B
Pubblicato in Curr Protoc Hum Genet (2014)

Assessment of Artificial MiRNA Architectures for Higher Knockdown Efficiencies without the Undesired Effects in Mice

di Miura, Hiromi, Inoko, Hidetoshi, Tanaka, Masafumi, Nakaoka, Hirofumi, Kimura, Minoru, Gurumurthy, Channabasavaiah B., Sato, Masahiro, Ohtsuka, Masato
Pubblicato in PLoS One (2015)

Genetically modified mouse models to help fight COVID-19

di Gurumurthy, Channabasavaiah B, Quadros, Rolen M, Richardson, Guy P, Poluektova, Larisa Y, Mansour, Suzanne L, Ohtsuka, Masato
Pubblicato in Nat Protoc (2020)

Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis

di Huang, Kai, Zhang, Jingjing, O'Neill, Katelyn L., Gurumurthy, Channabasavaiah B., Quadros, Rolen M., Tu, Yaping, Luo, Xu
Pubblicato in J Biol Chem (2016)

CRISPR: a Versatile Tool for Both Forward and Reverse Genetics Research

di Gurumurthy, Channabasavaiah B., Grati, M'hamed, Ohtsuka, Masato, Schilit, Samantha L.P., Quadros, Rolen M., Liu, Xue Zhong
Pubblicato in Hum Genet (2016)

Generation and characterization of a P2rx2 V60L mouse model for DFNA41

di Chen, Xiaoya, Abad, Clemer, Chen, Zheng-yi, Young, Juan I, Gurumurthy, Channabasavaiah B, Walz, Katherina, Liu, Xue Zhong
Pubblicato in Hum Mol Genet (2021)