Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model

Retinoblastoma 1 (Rb1) is an essential gene regulating cellular proliferation, differentiation, and homeostasis. To exert these functions, Rb1 is recruited and physically interacts with a growing variety of signaling pathways. While Rb1 does not appear to be ubiquitously expressed, its expression ha...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Tarang, Shikha, Doi, Songila M. S. R., Gurumurthy, Channabasavaiah B., Harms, Donald, Quadros, Rolen, Rocha-Sanchez, Sonia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337335/
https://ncbi.nlm.nih.gov/pubmed/25755634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00052
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