A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor

door Loeuillet, Corinne, Touquet, Bastien, Guichou, Jean François, Labesse, Gilles, Sereno, Denis
Gepubliceerd in Int J Mol Sci (2019)

Comparing Binding Modes of Analogous Fragments Using NMR in Fragment-Based Drug Design: Application to PRDX5

door Aguirre, Clémentine, Brink, Tim ten, Guichou, Jean-François, Cala, Olivier, Krimm, Isabelle
Gepubliceerd in 2014

Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA

door Eldin, Patrick, Chazal, Nathalie, Fenard, David, Bernard, Eric, Guichou, Jean-François, Briant, Laurence
Gepubliceerd in 2014

Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study

door Kaplan, Elise, Guichou, Jean-François, Chaloin, Laurent, Kunzelmann, Simone, Leban, Nadia, Serpersu, Engin H., Lionne, Corinne
Gepubliceerd in Biochim Biophys Acta (2016)

Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention

door Ahmed-Belkacem, Abdelhakim, Guichou, Jean-François, Brillet, Rozenn, Ahnou, Nazim, Hernandez, Eva, Pallier, Coralie, Pawlotsky, Jean-Michel
Gepubliceerd in 2014

Nuclear receptor ligand-binding domains: reduction of helix H12 dynamics to favour crystallization

door Nahoum, Virginie, Lipski, Alexandra, Quillard, Fabien, Guichou, Jean-François, Boublik, Yvan, Pérez, Efrèn, Germain, Pierre, de Lera, Angel R., Bourguet, William
Gepubliceerd in 2008

Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity

door Sagnol, Sébastien, Yang, Yinshan, Bessin, Yannick, Allemand, Fréderic, Hapkova, Ilona, Notarnicola, Cécile, Guichou, Jean-François, Faure, Sandrine, Labesse, Gilles, de Santa Barbara, Pascal
Gepubliceerd in 2014

Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis

door Guca, Ewelina, Nagy, Gergely N., Hajdú, Fanni, Marton, Lívia, Izrael, Richard, Hoh, François, Yang, Yinshan, Vial, Henri, Vértessy, Beata G., Guichou, Jean-François, Cerdan, Rachel
Gepubliceerd in Sci Rep (2018)

Structural basis for chemically-induced homodimerization of a single domain antibody

door Lesne, Jean, Chang, Hung-Ju, De Visch, Angelique, Paloni, Matteo, Barthe, Philippe, Guichou, Jean-François, Mayonove, Pauline, Barducci, Alessandro, Labesse, Gilles, Bonnet, Jerome, Cohen-Gonsaud, Martin
Gepubliceerd in Sci Rep (2019)

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

door Ahmed-Belkacem, Abdelhakim, Colliandre, Lionel, Ahnou, Nazim, Nevers, Quentin, Gelin, Muriel, Bessin, Yannick, Brillet, Rozenn, Cala, Olivier, Douguet, Dominique, Bourguet, William, Krimm, Isabelle, Pawlotsky, Jean-Michel, Guichou, Jean- François
Gepubliceerd in Nat Commun (2016)

The ellagitannin metabolite urolithin C is a glucose‐dependent regulator of insulin secretion through activation of L‐type calcium channels

door Bayle, Morgane, Neasta, Jérémie, Dall'Asta, Margherita, Gautheron, Guillaume, Virsolvy, Anne, Quignard, Jean‐François, Youl, Estelle, Magous, Richard, Guichou, Jean‐François, Crozier, Alan, Del Rio, Daniele, Cros, Gérard, Oiry, Catherine
Gepubliceerd in Br J Pharmacol (2019)

Characterization of the Anti-Hepatitis C Virus Activity of New Nonpeptidic Small-Molecule Cyclophilin Inhibitors with the Potential for Broad Anti-Flaviviridae Activity

door Nevers, Quentin, Ruiz, Isaac, Ahnou, Nazim, Donati, Flora, Brillet, Rozenn, Softic, Laurent, Chazal, Maxime, Jouvenet, Nolwenn, Fourati, Slim, Baudesson, Camille, Bruscella, Patrice, Gelin, Muriel, Guichou, Jean-François, Pawlotsky, Jean-Michel, Ahmed-Belkacem, Abdelhakim
Gepubliceerd in Antimicrob Agents Chemother (2018)

Nuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV Replication

door Lahaye, Xavier, Satoh, Takeshi, Gentili, Matteo, Cerboni, Silvia, Silvin, Aymeric, Conrad, Cécile, Ahmed-Belkacem, Abdelhakim, Rodriguez, Elisa C., Guichou, Jean-François, Bosquet, Nathalie, Piel, Matthieu, Le Grand, Roger, King, Megan C., Pawlotsky, Jean-Michel, Manel, Nicolas
Gepubliceerd in Cell Rep (2016)

Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface

door Gibault, Floriane, Coevoet, Mathilde, Sturbaut, Manon, Farce, Amaury, Renault, Nicolas, Allemand, Frédéric, Guichou, Jean-François, Drucbert, Anne-Sophie, Foulon, Catherine, Magnez, Romain, Thuru, Xavier, Corvaisier, Matthieu, Huet, Guillemette, Chavatte, Philippe, Melnyk, Patricia, Bailly, Fabrice, Cotelle, Philippe
Gepubliceerd in Cancers (Basel) (2018)

Proceedings of the Frontiers of Retrovirology Conference 2016

door Zurnic, Irena, Hütter, Sylvia, Lehmann, Ute, Stanke, Nicole, Reh, Juliane, Kern, Tobias, Lindel, Fabian, Gerresheim, Gesche, Hamann, Martin, Müllers, Erik, Lesbats, Paul, Cherepanov, Peter, Serrao, Erik, Engelman, Alan, Lindemann, Dirk, Da Silva Santos, Claire, Tartour, Kevin, Cimarelli, Andrea, Burdick, Rya, Chen, Jianbo, Sastri, Jaya, Hu, Wei-Shau, Pathak, Vinay, Keppler, Oliver T., Pradeau, Karine, Eiler, Sylvia, Levy, Nicolas, Lennon, Sarah, Cianferani, Sarah, Emiliani, Stéphane, Ruff, Marc, Parissi, Vincent, Rato, Sylvie, Rausell, Antonio, Munoz, Miguel, Telenti, Amalio, Ciuffi, Angela, Zhyvoloup, Alexander, Melamed, Anat, Anderson, Ian, Planas, Delphine, Kriston-Vizi, Janos, Ketteler, Robin, Lee, Chen- Hsuin, Merritt, Andy, Ancuta, Petronela, Bangham, Charles, Fassati, Ariberto, Rodari, Anthony, Van Driessche, Benoit, Galais, Mathilde, Delacourt, Nadége, Fauquenoy, Sylvain, Vanhulle, Caroline, Kula, Anna, Burny, Arsène, Rohr, Olivier, Van Lint, Carine, van Montfort, Thijs, van der Sluis, Renee, Speijer, Dave, Berkhout, Ben, Meng, Bo, Rutkowski, Andrzej, Berry, Neil, Dölken, Lars, Lever, Andrew, Schuster, Thomas, Asbach, Benedikt, Wagner, Ralf, Gross, Christine, Wiesmann, Veit, Kalmer, Martina, Wittenberg, Thomas, Gettemans, Jan, Thoma-Kress, Andrea K., Li, Minghua, Freed, Eric O., Liu, Shan-Lu, Müller, Janis, Münch, Jan, Sewald, Xaver, Uchil, Pradeep, Ladinsky, Mark, Beloor, Jagadish, Pi, Ruoxi, Herrmann, Christin, Motamedi, Nasim, Murooka, Thomas, Brehm, Michael, Greiner, Dale, Mempel, Thorsten, Bjorkman, Pamela, Kumar, Priti, Mothes, Walther, Joas, Simone, Parrish, Erica, Gnanadurai, Clement Wesley, Lump, Edina, Stürzel, Christina M., Parrish, Nicholas F., Sauermann, Ulrike, Töpfer, Katharina, Schultheiss, Tina, Bosinger, Steven, Silvestri, Guido, Apetrei, Cristian, Huot, Nicholas, Müller-Trutwin, Michaela, Sauter, Daniel, Hahn, Beatrice H., Stahl-Hennig, Christiane, Kirchhoff, Frank, Schumann, Gerald, Jung-Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Canadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Gerdes, Patricia, Merkert, Sylvia, Pulgarin, Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, J., Faulkner, Geoffrey J., Hurst, Tara, Katzourakis, Aris, Magiorkinis, Gkikas, Schott, Kerstin, Derua, Rita, Seifried, Janna, Reuter, Andreas, Schmitz, Heike, Tondera, Christiane, Brandariz-Nuñez, Alberto, Diaz-Griffero, Felipe, Janssens, Veerle, König, Renate, Baldauf, Hanna-Mari, Stegmann, Lena, Schwarz, Sarah-Marie, Trotard, Maud, Martin, Margarethe, Lenzi, Gina, Burggraf, Manja, Pan, Xiaoyu, Fregoso, Oliver I., Lim, Efrem S., Abraham, Libin, Erikson, Elina, Nguyen, Laura, Ambiel, Ina, Rutsch, Frank, Kim, Baek, Emerman, Michael, Fackler, Oliver T., Wittmann, Sabine, Behrendt, Rayk, Volkmann, Bianca, Eissmann, Kristin, Gramberg, Thomas, Bolduan, Sebastian, Koppensteiner, Herwig, Regensburg, Stefanie, Brack-Werner, Ruth, Draenert, Rika, Schindler, Michael, Ducroux, Aurélie, Xu, Shuting, Ponnurangam, Aparna, Franz, Sergej, Malassa, Angelina, Ewald, Ellen, Goffinet, Christine, Fung, Sin-Yee, Chan, Ching-Ping, Yuen, Chun-Kit, Kok, Kin-Hang, Chan, Chin-Ping, Jin, Dong-Yan, Dittmer, Ulf, Kmiec, Dorota, Iyer, Shilpa, Stürzel, Christina, Hahn, Beatrice, Ariumi, Yasuo, Yasuda-Inoue, Mariko, Kawano, Koudai, Tateishi, Satoshi, Turelli, Priscilla, Compton, Alex, Roy, Nicolas, Porrot, Françoise, Billet, Anne, Casartelli, Nicoletta, Yount, Jacob, Liang, Chen, Schwartz, Oliver, Magnus, Carsten, Reh, Lucia, Moore, Penny, Uhr, Therese, Weber, Jacqueline, Morris, Lynn, Trkola, Alexandra, Grindberg, Rashel V., Schlaepfer, Erika, Schreiber, Gideon, Simon, Viviana, Speck, Roberto F., Debyser, Zeger, Vranckx, Lenard, Demeulemeester, Jonas, Saleh, Suha, Verdin, Eric, Cereseto, Anna, Christ, Frauke, Gijsbers, Rik, Wang, Gang, Zhao, Na, Das, Atze T., Köstler, Josef, Perdiguero, Beatriz, Esteban, Mariano, Jacobs, Bertram L., Montefiori, David C., LaBranche, Celia C., Yates, Nicole L., Tomaras, Georgia D., Ferrari, Guido, Foulds, Kathryn E., Roederer, Mario, Landucci, Gary, Forthal, Donald N., Seaman, Michael S., Hawkins, Natalie, Self, Steven G., Phogat, Sanjay, Tartaglia, James, Barnett, Susan W., Burke, Brian, Cristillo, Anthony D., Ding, Song, Heeney, Jonathan L., Pantaleo, Giuseppe, Stab, Viktoria, Ensser, Armin, Tippler, Bettina, Burton, Dennis, Tenbusch, Matthias, Überla, Klaus, Alter, Galit, Lofano, Giuseppe, Dugast, Anne-Sophie, Kulkarni, Viraj, Suscovich, Todd, Opazo, Tatiana, Barraza, Felipe, Herrera, Diego, Garces, Andrea, Schwenke, Tomas, Tapia, Diego, Cancino, Jorge, Arriagada, Gloria, Haußner, Christina, Damm, Dominik, Rohrhofer, Anette, Schmidt, Barbara, Eichler, Jutta, Midgley, Rebecca, Wheeldon, James, Piguet, Vincent, Khopkar, Priyanka, Rohamare, Megha, Kulkarni, Smita, Godinho-Santos, Ana, Hance, Allan, Goncalves, Joao, Mammano, Fabrizio, Gasser, Romain, Hamoudi, Meriem, Pellicciotta, Martina, Zhou, Zhicheng, Visdeloup, Clara, Colin, Philippe, Braibant, Martine, Lagane, Bernard, Negroni, Matteo, Wamara, Jula, Bannert, Norbert, Mesplede, Thibault, Osman, Nathan, Anstett, Kaitlin, Liang, Jiaming Calvin, Pham, Hanh Thi, Wainberg, Mark, Shao, Wei, Shan, Jigui, Kearney, Mary, Wu, Xiaolin, Maldarelli, Frank, Mellors, John, Luke, Brian, Coffin, John, Hughes, Stephen, Fricke, Thomas, Opp, Silvana, Shepard, Caitlin, Ivanov, Dmitri, Valle-Casuso, Jose, Kanja, Marine, Cappy, Pierre, Negroni, Matteo, Lener, Daniela, Knyazhanskaya, Ekaterina, Anisenko, Andrey, Zatsepin, Timofey, Gottikh, Marina, Komkov, Alexander, Minervina, Anastasia, Nugmanov, Gaiaz, Nazarov, Vadim, Khodosevich, Konstantin, Mamedov, Ilgar, Lebedev, Yuri, Colomer-Lluch, Marta, Serra-Moreno, Ruth, Sarracino, Ambra, Gharu, Lavina, Pasternak, Alexander, Marcello, Alessandro, McCartin, Ann Marie, Kulkarni, Anurag, Le Douce, Valentin, Gautier, Virginie, Baeyens, Ann, Naessens, Evelien, Van Nuffel, Anouk, Weening, Karin, Reilly, Anne- Marie, Claeys, Eva, Trypsteen, Wim, Vandekerckhove, Linos, Eyckerman, Sven, Gevaert, Kris, Verhasselt, Bruno, Mok, Hoi Ping, Norton, Nicholas, Fun, Axel, Hirst, Jack, Wills, Mark, Miklik, Dalibor, Senigl, Filip, Hejnar, Jiri, Sakuragi, Jun-ichi, Sakuragi, Sayuri, Yokoyama, Masaru, Shioda, Tatsuo, Sato, Hironori, Bodem, Jochen, Moschall, Rebecca, Denk, Sarah, Erkelenz, Steffen, Schenk, Christian, Schaal, Heiner, Donhauser, Norbert, Socher, Ellen, Millen, Sebastian, Sticht, Heinrich, Gross, Christine, Mann, Melanie, Wei, Guochao, Betts, Matthew J., Liu, Yang, Kehl, Timo, Russell, Robert B., Löchelt, Martin, Hohn, Oliver, Mostafa, Saeed, Hanke, Kirsten, Norley, Stephen, Chen, Chia-Yen, Shingai, Masashi, Borrego, Pedro, Taveira, Nuno, Strebel, Klaus, Hellmund, Chris, Meng, Bo, Friedrich, Melanie, Hahn, Friedrich, Setz, Christian, Rauch, Pia, Fraedrich, Kirsten, Matthaei, Alina, Henklein, Petra, Traxdorf, Maximilian, Fossen, Torgils, Schubert, Ulrich, Khwaja, Aya, Galilee, Meytal, Alian, Akram, Schwalbe, Birco, Hauser, Heiko, Schreiber, Michael, Scherpenisse, Mirte, Cho, Young-Keol, Kim, Jungeun, Jeong, Daeun, Trejbalova, Katerina, Benesova, Martina, Kucerova, Dana, Vernerova, Zdenka, Amouroux, Rachel, Hajkova, Petra, Elleder, Daniel, Hron, Tomas, Farkasova, Helena, Padhi, Abinash, Paces, Jan, Zhu, Henan, Gifford, Robert, Murcia, Pablo, Carrozza, Maria Luisa, Niewiadomska, Anna-Maria, Mazzei, Maurizio, Abi-Said, Mounir, Hughes, Joseph, Hué, Stéphane, Gifford, Robert, Obasa, Adetayo, Jacobs, Graeme, Engelbrecht, Susan, Mack, Katharina, Starz, Kathrin, Geyer, Matthias, Bibollet-Ruche, Frederic, Stürzel, Christina, Leoz, Marie, Plantier, Jean Christophe, Argaw-Denboba, Ayele, Balestrieri, Emanuela, Serafino, Annalucia, Bucci, Ilaria, Cipriani, Chiara, Spadafora, Corrado, Sinibaldi-Vallebona, Paolo, Matteucci, Claudia, Jayashree, S. Nandi, Neogi, Ujjwal, Chhangani, Anil K., Rathore, Shravan Sing, Mathur, Bajrang R. J., Abati, Adeyemi, Koç, B. Taylan, Oğuzoğlu, Tuba Çiğdem, Shimauchi, Takatoshi, Caucheteux, Stephan, Turpin, Jocelyn, Finsterbusch, Katja, Tokura, Yoshiki, Souriant, Shanti, Balboa, Luciana, Pingris, Karine, Kviatcowsky, Denise, Raynaud-Messina, Brigitte, Cougoule, Céline, Mercier, Ingrid, Kuroda, Marcelo, González-Montaner, Pablo, Inwentarz, Sandra, Moraña, Eduardo Jose, del Carmen Sasiain, Maria, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Lugo-Villarino, Geanncarlo, Vérollet, Christel, Herrmann, Alexandra, Thomas, Dominique, Bouzas, Nerea Ferreirós, Lahaye, Xavier, Bhargava, Anvita, Satoh, Takeshi, Gentili, Matteo, Cerboni, Silvia, Silvin, Aymeric, Conrad, Cécile, Ahmed-Belkacem, Hakim, Rodriguez, Elisa C., Guichou, Jean-François, Bosquet, Nathalie, Piel, Matthieu, Le Grand, Roger, King, Megan, Pawlotsky, Jean-Michel, Manel, Nicolas, Hofmann, Henning, Vanwalscappel, Benedicte, Bloch, Nicolin, Landau, Nathaniel, Indik, Stanislav, Hagen, Benedikt, Valle-Casuso, José Carlos, Allouch, Awatef, David, Annie, Barré-Sinoussi, Françoise, Benkirane, Monsef, Pancino, Gianfranco, Saez-Cirion, Asier, Lee, Wing-Yiu, Sloan, Richard, Schulte, Bianca, Opp, Silvana, Blomberg, Jonas, Vargiu, Luana, Rodriguez-Tomé, Patricia, Tramontano, Enzo, Sperber, Göran, Kumari, Namita, Ammosova, Tatiana, Diaz, Sharmeen, Oneal, Patricia, Nekhai, Sergei, Fahrny, Audrey, Gers-Huber, Gustavo, Audigé, Annette, Jayaprakash, Anitha, Sachidanandam, Ravi, Hernandez, Matt, Dillon-White, Marsha, Souriant, Shanti, Pingris, Karine, Raynaud-Messina, Brigitte, Cougoule, Céline, Mercier, Ingrid, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Lugo-Villarino, Geanncarlo, Maze, Emmanuel, Ham, Claire, Almond, Neil, Towers, Greg, Belshaw, Robert, de Sousa-Pereira, Patrícia, Abrantes, Joana, Pizzato, Massimo, Esteves, Pedro J., Kahle, Tanja, Schmitt, Sven, Merkel, Laura, Reuter, Nina, Stamminger, Thomas, Rosa, Ilaria Dalla, Bishop, Kate, Spinazzola, Antonella, Groom, Harriet, Vieyres, Gabrielle, Müsken, Mathias, Zillinger, Thomas, Hornung, Veit, Barchet, Winfried, Häussler, Susanne, Pietschmann, Thomas, Javed, Aneela, Leuchte, Nicole, Salinas, Gabriela, Opitz, Lennart, Sopper, Sieghart, Mummert, Christiane, Hofmann, Christian, Hückelhoven, Angela G., Bergmann, Silke, Müller-Schmucker, Sandra M., Harrer, Ellen G., Dörrie, Jan, Schaft, Niels, Harrer, Thomas, Cardinaux, Laure, Zahno, M.- L., Vogt, H.- R., Zanoni, R., Bertoni, G., Muenchhoff, Maximilian, Goulder, Philip, Keppler, Oliver, Rebensburg, Stephanie, Helfer, Markus, Zhang, Yuwei, Chen, Huicheng, Bernier, Annie, Gosselin, Annie, Routy, Jean- Pierre, Wöhrl, Birgitta, Schneider, Anna, Corona, Angela, Spöring, Imke, Jordan, Mareike, Buchholz, Bernd, Maccioni, Elias, Di Santo, Roberto, Schweimer, Kristian, Schölz, Christian, Weinert, Brian, Wagner, Sebastian, Beli, Petra, Miyake, Yasuyuki, Qi, Jun, Jensen, Lars, Streicher, Werner, McCarthy, Anna, Westwood, Nicholas, Lain, Sonia, Cox, Jürgen, Matthias, Patrick, Mann, Matthias, Bradner, James, Choudhary, Chunaram, Stern, Marcel, Valletta, Elena, Frezza, Caterina, Marino-Merlo, Francesca, Grelli, Sandro, Serafino, Anna Lucia, Mastino, Antonio, Macchi, Beatrice, Kaulfuß, Meike, Windmann, Sonja, Bayer, Wibke, Mikasi, Sello, Jacobs, Graeme, Heß, Rebecca, Bonsmann, Michael Storcksdieck gen., Kirschning, Carsten, Lepenies, Bernd, Kolenbrander, Anne, Temchura, Vladimir, Iijima, Kenta, Kobayashi, Junya, Ishizaka, Yukihito
Gepubliceerd in Retrovirology (2016)