THE HEPARAN SULFATE PROTEOGLYCAN GRIP ON HYPERLIPIDEMIA AND ATHEROSCLEROSIS

по Gordts, Philip L.S.M., Esko, Jeffrey D.
Опубликовано в: Matrix Biol (2018)

A Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgR(KT) to the List

по Yeang, Calvin, Gordts, Philip L.S.M., Tsimikas, Sotirios
Опубликовано в: Circ Res (2017)

Reply to Soulillou et al.: Difficulties in extrapolating from animal models exemplify unusual human atherosclerosis susceptibility and mechanisms via CMAH loss

по Kawanishi, Kunio, Dhar, Chirag, Varki, Ajit, Gordts, Philip L. S. M.
Опубликовано в: Proc Natl Acad Sci U S A (2020)

Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation

по Pessentheiner, Ariane R., Ducasa, G. Michelle, Gordts, Philip L. S. M.
Опубликовано в: Front Immunol (2020)

Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell–Matrix Interface

по Trieger, Greg W., Verespy, Stephen, Gordts, Philip L. S. M., Godula, Kamil
Опубликовано в: Bioconjug Chem (2019)

Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms

по Clark, Alex E., Sabalza, Maite, Gordts, Philip L. S. M., Spector, Deborah H.
Опубликовано в: J Virol (2018)

Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

по Gonzales, Jon C., Gordts, Philip L.S.M., Foley, Erin M., Esko, Jeffrey D.
Опубликовано 2013

Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

по Kawanishi, Kunio, Dhar, Chirag, Do, Raymond, Varki, Nissi, Gordts, Philip L. S. M., Varki, Ajit
Опубликовано в: Proc Natl Acad Sci U S A (2019)

Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

по Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Опубликовано в: Glycobiology (2019)

Corrigendum to: Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

по Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Опубликовано в: Glycobiology (2020)

Shedding of syndecan-1 from human hepatocytes alters VLDL clearance

по Deng, Yiping, Foley, Erin M., Gonzales, Jon C., Gordts, Philip L., Li, Yulin, Esko, Jeffrey D.
Опубликовано 2011

Small molecule antagonists of cell-surface heparan sulfate and heparin–protein interactions

по Weiss, Ryan J., Gordts, Philip L. S. M., Le, Dzung, Xu, Ding, Esko, Jeffrey D., Tor, Yitzhak
Опубликовано в: Chem Sci (2015)

A Genetic Model of Substrate Reduction Therapy for Mucopolysaccharidosis

по Lamanna, William C., Lawrence, Roger, Sarrazin, Stéphane, Lameda-Diaz, Carlos, Gordts, Philip L. S. M., Moremen, Kelley W., Esko, Jeffrey D.
Опубликовано 2012

Hepatic Remnant Lipoprotein Clearance by Heparan Sulfate Proteoglycans and Low-Density Lipoprotein Receptors Depend on Dietary Conditions in Mice

по Foley, Erin M., Gordts, Philip L.S.M., Stanford, Kristin I., Gonzales, Jon C., Lawrence, Roger, Stoddard, Nicole, Esko, Jeffrey D.
Опубликовано 2013

Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

по Gordts, Philip L.S.M., Bartelt, Alexander, Nilsson, Stefan K., Annaert, Wim, Christoffersen, Christina, Nielsen, Lars Bo, Heeren, Joerg, Roebroek, Anton J.M.
Опубликовано 2012

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

по Fischer, Alexander W., Albers, Kirstin, Krott, Lucia M., Hoffzimmer, Britta, Heine, Markus, Schmale, Hartwig, Scheja, Ludger, Gordts, Philip L.S.M., Heeren, Joerg
Опубликовано в: Mol Metab (2018)

PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles

по Fischer, Alexander W., Albers, Kirstin, Schlein, Christian, Sass, Frederike, Krott, Lucia M., Schmale, Hartwig, Gordts, Philip L.S.M., Scheja, Ludger, Heeren, Joerg
Опубликовано в: Biochim Biophys Acta Mol Basis Dis (2019)

Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I

по Khalid, Omar, Vera, Moin U., Gordts, Philip L., Ellinwood, N. Matthew, Schwartz, Philip H., Dickson, Patricia I., Esko, Jeffrey D., Wang, Raymond Y.
Опубликовано в: PLoS One (2016)

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

по Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Опубликовано в: J Biol Chem (2019)

Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice.

по Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Опубликовано в: J Biol Chem (2020)