Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity

Por Wagner, Tobias, Bartelt, Alexander, Schlein, Christian, Heeren, Joerg
Publicado no PLoS One (2015)

Intact innervation is essential for diet-induced recruitment of brown adipose tissue

Por Fischer, Alexander W., Schlein, Christian, Cannon, Barbara, Heeren, Joerg, Nedergaard, Jan
Publicado no Am J Physiol Endocrinol Metab (2019)

Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression

Por Worthmann, Anna, Schlein, Christian, Berbée, Jimmy F. P., Rensen, Patrick C. N., Heeren, Joerg, Bartelt, Alexander
Publicado no Nutrients (2019)

Thermoneutrality-Induced Macrophage Accumulation in Brown Adipose Tissue Does Not Impair the Tissue’s Competence for Cold-Induced Thermogenic Recruitment

Por Fischer, Alexander W., de Jong, Jasper M. A., Sass, Frederike, Schlein, Christian, Heeren, Joerg, Petrovic, Natasa
Publicado no Front Endocrinol (Lausanne) (2020)

Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice

Por Fischer, Alexander W., Behrens, Janina, Sass, Frederike, Schlein, Christian, Heine, Markus, Pertzborn, Paul, Scheja, Ludger, Heeren, Joerg
Publicado no J Lipid Res (2020)

PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles

Por Fischer, Alexander W., Albers, Kirstin, Schlein, Christian, Sass, Frederike, Krott, Lucia M., Schmale, Hartwig, Gordts, Philip L.S.M., Scheja, Ludger, Heeren, Joerg
Publicado no Biochim Biophys Acta Mol Basis Dis (2019)

TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

Por Sass, Frederike, Schlein, Christian, Jaeckstein, Michelle Y., Pertzborn, Paul, Schweizer, Michaela, Schinke, Thorsten, Ballabio, Andrea, Scheja, Ludger, Heeren, Joerg, Fischer, Alexander W.
Publicado no Mol Metab (2021)

FoxO transcription factors are required for hepatic HDL cholesterol clearance

Por Lee, Samuel X., Heine, Markus, Schlein, Christian, Ramakrishnan, Rajasekhar, Liu, Jing, Belnavis, Gabriella, Haimi, Ido, Fischer, Alexander W., Ginsberg, Henry N., Heeren, Joerg, Rinninger, Franz, Haeusler, Rebecca A.
Publicado no J Clin Invest (2018)

Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity

Por Chen, Yong, Buyel, Joschka J., Hanssen, Mark J. W., Siegel, Franziska, Pan, Ruping, Naumann, Jennifer, Schell, Michael, van der Lans, Anouk, Schlein, Christian, Froehlich, Holger, Heeren, Joerg, Virtanen, Kirsi A., van Marken Lichtenbelt, Wouter, Pfeifer, Alexander
Publicado no Nat Commun (2016)

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Por Bartelt, Alexander, Widenmaier, Scott B., Schlein, Christian, Johann, Kornelia, Goncalves, Renata L. S., Eguchi, Kosei, Fischer, Alexander W., Parlakgül, Günes, Snyder, Nicole A., Nguyen, Truc B., Bruns, Oliver T., Franke, Daniel, Bawendi, Moungi G., Lynes, Matthew D., Leiria, Luiz O., Tseng, Yu-Hua, Inouye, Karen E., Arruda, Ana Paula, Hotamisligil, Gökhan S.
Publicado no Nat Med (2018)

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution

Por Schlein, Christian, Fischer, Alexander W., Sass, Frederike, Worthmann, Anna, Tödter, Klaus, Jaeckstein, Michelle Y., Behrens, Janina, Lynes, Matthew D., Kiebish, Michael A., Narain, Niven R., Bussberg, Val, Darkwah, Abena, Jespersen, Naja Zenius, Nielsen, Søren, Scheele, Camilla, Schweizer, Michaela, Braren, Ingke, Bartelt, Alexander, Tseng, Yu-Hua, Heeren, Joerg, Scheja, Ludger
Publicado no Cell Rep (2021)

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Por Bartelt, Alexander, John, Clara, Schaltenberg, Nicola, Berbée, Jimmy F. P., Worthmann, Anna, Cherradi, M. Lisa, Schlein, Christian, Piepenburg, Julia, Boon, Mariëtte R., Rinninger, Franz, Heine, Markus, Toedter, Klaus, Niemeier, Andreas, Nilsson, Stefan K., Fischer, Markus, Wijers, Sander L., van Marken Lichtenbelt, Wouter, Scheja, Ludger, Rensen, Patrick C. N., Heeren, Joerg
Publicado no Nat Commun (2017)

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

Por Berbée, Jimmy F. P., Boon, Mariëtte R, Khedoe, P. Padmini S. J., Bartelt, Alexander, Schlein, Christian, Worthmann, Anna, Kooijman, Sander, Hoeke, Geerte, Mol, Isabel M., John, Clara, Jung, Caroline, Vazirpanah, Nadia, Brouwers, Linda P.J., Gordts, Philip L.S.M., Esko, Jeffrey D., Hiemstra, Pieter S., Havekes, Louis M., Scheja, Ludger, Heeren, Joerg, Rensen, Patrick C.N.
Publicado no Nat Commun (2015)

The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

Por Lynes, Matthew D, Leiria, Luiz O, Lundh, Morten, Bartelt, Alexander, Shamsi, Farnaz, Huang, Tian Lian, Takahashi, Hirokazu, Hirshman, Michael F, Schlein, Christian, Lee, Alexandra, Baer, Lisa A, May, Francis J, Gao, Fei, Narain, Niven R, Chen, Emily Y, Kiebish, Michael A, Cypess, Aaron M, Blüher, Matthias, Goodyear, Laurie J, Hotamisligil, Gökhan S, Stanford, Kristin I, Tseng, Yu-Hua
Publicado no Nat Med (2017)

Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

Por Lynes, Matthew D, Leiria, Luiz O, Lundh, Morten, Bartelt, Alexander, Shamsi, Farnaz, Huang, Tian Lian, Takahashi, Hirokazu, Hirshman, Michael F, Schlein, Christian, Lee, Alexandra, Baer, Lisa A, May, Francis J, Gao, Fei, Narain, Niven R, Chen, Emily Y, Kiebish, Michael A, Cypess, Aaron M, Blüher, Matthias, Goodyear, Laurie J, Hotamisligil, Gökhan S, Stanford, Kristin I, Tseng, Yu-Hua
Publicado no Nat Med (2017)