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PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles

The phosphotyrosine interacting domain-containing protein 1 (PID1) serves as a cytosolic adaptor protein of the LDL receptor-related protein 1 (LRP1). By regulating its intracellular trafficking, PID1 controls the hepatic, LRP1-dependent clearance of pro-atherogenic lipoproteins. In adipose and musc...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta Mol Basis Dis
Auteurs principaux: Fischer, Alexander W., Albers, Kirstin, Schlein, Christian, Sass, Frederike, Krott, Lucia M., Schmale, Hartwig, Gordts, Philip L.S.M., Scheja, Ludger, Heeren, Joerg
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624118/
https://ncbi.nlm.nih.gov/pubmed/30904610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.03.010
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