The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

OBJECTIVE: Insulin resistance is associated with impaired receptor dependent hepatic uptake of triglyceride-rich lipoproteins (TRL), promoting hypertriglyceridemia and atherosclerosis. Next to low-density lipoprotein (LDL) receptor (LDLR) and syndecan-1, the LDLR-related protein 1 (LRP1) stimulated...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Fischer, Alexander W., Albers, Kirstin, Krott, Lucia M., Hoffzimmer, Britta, Heine, Markus, Schmale, Hartwig, Scheja, Ludger, Gordts, Philip L.S.M., Heeren, Joerg
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158030/
https://ncbi.nlm.nih.gov/pubmed/30100244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.07.010
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