The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

Brown adipose tissue (BAT) and beige adipose tissue combust fuels for heat production in adult humans, and so constitute an appealing target for the treatment of metabolic disorders such as obesity, diabetes and hyperlipidemia(1,2). Cold exposure can enhance energy expenditure by activating BAT, and...

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Published in:Nat Med
Main Authors: Lynes, Matthew D, Leiria, Luiz O, Lundh, Morten, Bartelt, Alexander, Shamsi, Farnaz, Huang, Tian Lian, Takahashi, Hirokazu, Hirshman, Michael F, Schlein, Christian, Lee, Alexandra, Baer, Lisa A, May, Francis J, Gao, Fei, Narain, Niven R, Chen, Emily Y, Kiebish, Michael A, Cypess, Aaron M, Blüher, Matthias, Goodyear, Laurie J, Hotamisligil, Gökhan S, Stanford, Kristin I, Tseng, Yu-Hua
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699924/
https://ncbi.nlm.nih.gov/pubmed/28346411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4297
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