Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

Binding and uptake of triglyceride-rich lipoproteins (TRLs) in mice depend on heparan sulfate and the hepatic proteoglycan, syndecan-1 (SDC1). Alteration of glucosamine N-sulfation by deletion of glucosamine N-deacetylase-N-sulfotransferase 1 (Ndst1) and 2-O-sulfation of uronic acids by deletion of...

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Enregistré dans:
Détails bibliographiques
Publié dans:Glycobiology
Auteurs principaux: Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Glycan Metabolism
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639542/
https://ncbi.nlm.nih.gov/pubmed/31094413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz037
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