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Shedding of syndecan-1 from human hepatocytes alters VLDL clearance

We recently showed that the heparan sulfate proteoglycan syndecan-1 mediates hepatic clearance of triglyceride-rich lipoproteins in mice based on systemic deletion of syndecan-1 and hepatocyte-specific inactivation of sulfotransferases involved in heparan sulfate biosynthesis (MacArthur et al. (2007...

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Detalhes bibliográficos
Main Authors: Deng, Yiping, Foley, Erin M., Gonzales, Jon C., Gordts, Philip L., Li, Yulin, Esko, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245353/
https://ncbi.nlm.nih.gov/pubmed/21898481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24626
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