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Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans
The heparan sulfate proteoglycan (HSPG) syndecan-1 (SDC1) acts as a major receptor for triglyceride-rich lipoprotein (TRL) clearance in the liver. We sought to identify the relevant apolipoproteins on TRLs that mediate binding to SDC1 and determine their clinical relevance. Evidence supporting ApoE...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668842/ https://ncbi.nlm.nih.gov/pubmed/23676495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67398 |
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