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Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

The heparan sulfate proteoglycan (HSPG) syndecan-1 (SDC1) acts as a major receptor for triglyceride-rich lipoprotein (TRL) clearance in the liver. We sought to identify the relevant apolipoproteins on TRLs that mediate binding to SDC1 and determine their clinical relevance. Evidence supporting ApoE...

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書誌詳細
主要な著者: Gonzales, Jon C., Gordts, Philip L.S.M., Foley, Erin M., Esko, Jeffrey D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668842/
https://ncbi.nlm.nih.gov/pubmed/23676495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67398
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