THE HEPARAN SULFATE PROTEOGLYCAN GRIP ON HYPERLIPIDEMIA AND ATHEROSCLEROSIS

por Gordts, Philip L.S.M., Esko, Jeffrey D.
Publicado en Matrix Biol (2018)

A Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgR(KT) to the List

por Yeang, Calvin, Gordts, Philip L.S.M., Tsimikas, Sotirios
Publicado en Circ Res (2017)

Reply to Soulillou et al.: Difficulties in extrapolating from animal models exemplify unusual human atherosclerosis susceptibility and mechanisms via CMAH loss

por Kawanishi, Kunio, Dhar, Chirag, Varki, Ajit, Gordts, Philip L. S. M.
Publicado en Proc Natl Acad Sci U S A (2020)

Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation

por Pessentheiner, Ariane R., Ducasa, G. Michelle, Gordts, Philip L. S. M.
Publicado en Front Immunol (2020)

Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell–Matrix Interface

por Trieger, Greg W., Verespy, Stephen, Gordts, Philip L. S. M., Godula, Kamil
Publicado en Bioconjug Chem (2019)

Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms

por Clark, Alex E., Sabalza, Maite, Gordts, Philip L. S. M., Spector, Deborah H.
Publicado en J Virol (2018)

Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

por Gonzales, Jon C., Gordts, Philip L.S.M., Foley, Erin M., Esko, Jeffrey D.
Publicado 2013

Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

por Kawanishi, Kunio, Dhar, Chirag, Do, Raymond, Varki, Nissi, Gordts, Philip L. S. M., Varki, Ajit
Publicado en Proc Natl Acad Sci U S A (2019)

Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

por Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Publicado en Glycobiology (2019)

Corrigendum to: Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

por Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Publicado en Glycobiology (2020)

Shedding of syndecan-1 from human hepatocytes alters VLDL clearance

por Deng, Yiping, Foley, Erin M., Gonzales, Jon C., Gordts, Philip L., Li, Yulin, Esko, Jeffrey D.
Publicado 2011

Small molecule antagonists of cell-surface heparan sulfate and heparin–protein interactions

por Weiss, Ryan J., Gordts, Philip L. S. M., Le, Dzung, Xu, Ding, Esko, Jeffrey D., Tor, Yitzhak
Publicado en Chem Sci (2015)

A Genetic Model of Substrate Reduction Therapy for Mucopolysaccharidosis

por Lamanna, William C., Lawrence, Roger, Sarrazin, Stéphane, Lameda-Diaz, Carlos, Gordts, Philip L. S. M., Moremen, Kelley W., Esko, Jeffrey D.
Publicado 2012

Hepatic Remnant Lipoprotein Clearance by Heparan Sulfate Proteoglycans and Low-Density Lipoprotein Receptors Depend on Dietary Conditions in Mice

por Foley, Erin M., Gordts, Philip L.S.M., Stanford, Kristin I., Gonzales, Jon C., Lawrence, Roger, Stoddard, Nicole, Esko, Jeffrey D.
Publicado 2013

Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

por Gordts, Philip L.S.M., Bartelt, Alexander, Nilsson, Stefan K., Annaert, Wim, Christoffersen, Christina, Nielsen, Lars Bo, Heeren, Joerg, Roebroek, Anton J.M.
Publicado 2012

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

por Fischer, Alexander W., Albers, Kirstin, Krott, Lucia M., Hoffzimmer, Britta, Heine, Markus, Schmale, Hartwig, Scheja, Ludger, Gordts, Philip L.S.M., Heeren, Joerg
Publicado en Mol Metab (2018)

PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles

por Fischer, Alexander W., Albers, Kirstin, Schlein, Christian, Sass, Frederike, Krott, Lucia M., Schmale, Hartwig, Gordts, Philip L.S.M., Scheja, Ludger, Heeren, Joerg
Publicado en Biochim Biophys Acta Mol Basis Dis (2019)

Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I

por Khalid, Omar, Vera, Moin U., Gordts, Philip L., Ellinwood, N. Matthew, Schwartz, Philip H., Dickson, Patricia I., Esko, Jeffrey D., Wang, Raymond Y.
Publicado en PLoS One (2016)

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

por Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Publicado en J Biol Chem (2019)

Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice.

por Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Publicado en J Biol Chem (2020)