THE HEPARAN SULFATE PROTEOGLYCAN GRIP ON HYPERLIPIDEMIA AND ATHEROSCLEROSIS

par Gordts, Philip L.S.M., Esko, Jeffrey D.
Publié dans Matrix Biol (2018)

A Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgR(KT) to the List

par Yeang, Calvin, Gordts, Philip L.S.M., Tsimikas, Sotirios
Publié dans Circ Res (2017)

Reply to Soulillou et al.: Difficulties in extrapolating from animal models exemplify unusual human atherosclerosis susceptibility and mechanisms via CMAH loss

par Kawanishi, Kunio, Dhar, Chirag, Varki, Ajit, Gordts, Philip L. S. M.
Publié dans Proc Natl Acad Sci U S A (2020)

Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation

par Pessentheiner, Ariane R., Ducasa, G. Michelle, Gordts, Philip L. S. M.
Publié dans Front Immunol (2020)

Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell–Matrix Interface

par Trieger, Greg W., Verespy, Stephen, Gordts, Philip L. S. M., Godula, Kamil
Publié dans Bioconjug Chem (2019)

Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms

par Clark, Alex E., Sabalza, Maite, Gordts, Philip L. S. M., Spector, Deborah H.
Publié dans J Virol (2018)

Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

par Gonzales, Jon C., Gordts, Philip L.S.M., Foley, Erin M., Esko, Jeffrey D.
Publié 2013

Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

par Kawanishi, Kunio, Dhar, Chirag, Do, Raymond, Varki, Nissi, Gordts, Philip L. S. M., Varki, Ajit
Publié dans Proc Natl Acad Sci U S A (2019)

Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

par Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Publié dans Glycobiology (2019)

Corrigendum to: Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

par Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Publié dans Glycobiology (2020)

Shedding of syndecan-1 from human hepatocytes alters VLDL clearance

par Deng, Yiping, Foley, Erin M., Gonzales, Jon C., Gordts, Philip L., Li, Yulin, Esko, Jeffrey D.
Publié 2011

Small molecule antagonists of cell-surface heparan sulfate and heparin–protein interactions

par Weiss, Ryan J., Gordts, Philip L. S. M., Le, Dzung, Xu, Ding, Esko, Jeffrey D., Tor, Yitzhak
Publié dans Chem Sci (2015)

A Genetic Model of Substrate Reduction Therapy for Mucopolysaccharidosis

par Lamanna, William C., Lawrence, Roger, Sarrazin, Stéphane, Lameda-Diaz, Carlos, Gordts, Philip L. S. M., Moremen, Kelley W., Esko, Jeffrey D.
Publié 2012

Hepatic Remnant Lipoprotein Clearance by Heparan Sulfate Proteoglycans and Low-Density Lipoprotein Receptors Depend on Dietary Conditions in Mice

par Foley, Erin M., Gordts, Philip L.S.M., Stanford, Kristin I., Gonzales, Jon C., Lawrence, Roger, Stoddard, Nicole, Esko, Jeffrey D.
Publié 2013

Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

par Gordts, Philip L.S.M., Bartelt, Alexander, Nilsson, Stefan K., Annaert, Wim, Christoffersen, Christina, Nielsen, Lars Bo, Heeren, Joerg, Roebroek, Anton J.M.
Publié 2012

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

par Fischer, Alexander W., Albers, Kirstin, Krott, Lucia M., Hoffzimmer, Britta, Heine, Markus, Schmale, Hartwig, Scheja, Ludger, Gordts, Philip L.S.M., Heeren, Joerg
Publié dans Mol Metab (2018)

PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles

par Fischer, Alexander W., Albers, Kirstin, Schlein, Christian, Sass, Frederike, Krott, Lucia M., Schmale, Hartwig, Gordts, Philip L.S.M., Scheja, Ludger, Heeren, Joerg
Publié dans Biochim Biophys Acta Mol Basis Dis (2019)

Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I

par Khalid, Omar, Vera, Moin U., Gordts, Philip L., Ellinwood, N. Matthew, Schwartz, Philip H., Dickson, Patricia I., Esko, Jeffrey D., Wang, Raymond Y.
Publié dans PLoS One (2016)

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

par Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Publié dans J Biol Chem (2019)

Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice.

par Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Publié dans J Biol Chem (2020)