THE HEPARAN SULFATE PROTEOGLYCAN GRIP ON HYPERLIPIDEMIA AND ATHEROSCLEROSIS

von Gordts, Philip L.S.M., Esko, Jeffrey D.
Veröffentlicht in Matrix Biol (2018)

A Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgR(KT) to the List

von Yeang, Calvin, Gordts, Philip L.S.M., Tsimikas, Sotirios
Veröffentlicht in Circ Res (2017)

Reply to Soulillou et al.: Difficulties in extrapolating from animal models exemplify unusual human atherosclerosis susceptibility and mechanisms via CMAH loss

von Kawanishi, Kunio, Dhar, Chirag, Varki, Ajit, Gordts, Philip L. S. M.
Veröffentlicht in Proc Natl Acad Sci U S A (2020)

Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation

von Pessentheiner, Ariane R., Ducasa, G. Michelle, Gordts, Philip L. S. M.
Veröffentlicht in Front Immunol (2020)

Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell–Matrix Interface

von Trieger, Greg W., Verespy, Stephen, Gordts, Philip L. S. M., Godula, Kamil
Veröffentlicht in Bioconjug Chem (2019)

Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms

von Clark, Alex E., Sabalza, Maite, Gordts, Philip L. S. M., Spector, Deborah H.
Veröffentlicht in J Virol (2018)

Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

von Gonzales, Jon C., Gordts, Philip L.S.M., Foley, Erin M., Esko, Jeffrey D.
Veröffentlicht 2013

Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

von Kawanishi, Kunio, Dhar, Chirag, Do, Raymond, Varki, Nissi, Gordts, Philip L. S. M., Varki, Ajit
Veröffentlicht in Proc Natl Acad Sci U S A (2019)

Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

von Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Veröffentlicht in Glycobiology (2019)

Corrigendum to: Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants

von Anower-E-Khuda, Ferdous, Singh, Gagandeep, Deng, Yiping, Gordts, Philip L S M, Esko, Jeffrey D
Veröffentlicht in Glycobiology (2020)

Shedding of syndecan-1 from human hepatocytes alters VLDL clearance

von Deng, Yiping, Foley, Erin M., Gonzales, Jon C., Gordts, Philip L., Li, Yulin, Esko, Jeffrey D.
Veröffentlicht 2011

Small molecule antagonists of cell-surface heparan sulfate and heparin–protein interactions

von Weiss, Ryan J., Gordts, Philip L. S. M., Le, Dzung, Xu, Ding, Esko, Jeffrey D., Tor, Yitzhak
Veröffentlicht in Chem Sci (2015)

A Genetic Model of Substrate Reduction Therapy for Mucopolysaccharidosis

von Lamanna, William C., Lawrence, Roger, Sarrazin, Stéphane, Lameda-Diaz, Carlos, Gordts, Philip L. S. M., Moremen, Kelley W., Esko, Jeffrey D.
Veröffentlicht 2012

Hepatic Remnant Lipoprotein Clearance by Heparan Sulfate Proteoglycans and Low-Density Lipoprotein Receptors Depend on Dietary Conditions in Mice

von Foley, Erin M., Gordts, Philip L.S.M., Stanford, Kristin I., Gonzales, Jon C., Lawrence, Roger, Stoddard, Nicole, Esko, Jeffrey D.
Veröffentlicht 2013

Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

von Gordts, Philip L.S.M., Bartelt, Alexander, Nilsson, Stefan K., Annaert, Wim, Christoffersen, Christina, Nielsen, Lars Bo, Heeren, Joerg, Roebroek, Anton J.M.
Veröffentlicht 2012

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

von Fischer, Alexander W., Albers, Kirstin, Krott, Lucia M., Hoffzimmer, Britta, Heine, Markus, Schmale, Hartwig, Scheja, Ludger, Gordts, Philip L.S.M., Heeren, Joerg
Veröffentlicht in Mol Metab (2018)

PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles

von Fischer, Alexander W., Albers, Kirstin, Schlein, Christian, Sass, Frederike, Krott, Lucia M., Schmale, Hartwig, Gordts, Philip L.S.M., Scheja, Ludger, Heeren, Joerg
Veröffentlicht in Biochim Biophys Acta Mol Basis Dis (2019)

Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I

von Khalid, Omar, Vera, Moin U., Gordts, Philip L., Ellinwood, N. Matthew, Schwartz, Philip H., Dickson, Patricia I., Esko, Jeffrey D., Wang, Raymond Y.
Veröffentlicht in PLoS One (2016)

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

von Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Veröffentlicht in J Biol Chem (2019)

Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice.

von Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Veröffentlicht in J Biol Chem (2020)