Hypoxia Inducible Factors: Central Regulators of the Tumor Phenotype

par Gordan, John D., Simon, M. Celeste
Publié 2007

Tumor hepatitis B virus RNA identifies a clinically and molecularly distinct subset of hepatocellular carcinoma

par Lim, Huat Chye, Gordan, John D.
Publié dans PLoS Comput Biol (2021)

HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation

par Gordan, John D., Thompson, Craig B., Simon, M. Celeste
Publié 2007

Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma

par Huppert, Laura A., Gordan, John D., Kelley, Robin Kate
Publié dans Clin Liver Dis (Hoboken) (2020)

Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation

par Frazier, Nicole Michael, Brand, Toni, Gordan, John D., Grandis, Jennifer, Jura, Natalia
Publié dans Oncogene (2018)

The Keap1-BTB Protein Is an Adaptor That Bridges Nrf2 to a Cul3-Based E3 Ligase: Oxidative Stress Sensing by a Cul3-Keap1 Ligase

par Cullinan, Sara B., Gordan, John D., Jin, Jianping, Harper, J. Wade, Diehl, J. Alan
Publié 2004

HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity

par Gordan, John D., Bertovrt, Jessica A., Hu, Cheng-Jun, Diehl, J. Alan, Simon, M. Celeste
Publié 2007

Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism

par Young, Regina M., Wang, Shang-Jui, Gordan, John D., Ji, Xinjun, Liebhaber, Stephen A., Simon, M. Celeste
Publié 2008

An Optimized Chromatographic Strategy for Multiplexing In Parallel Reaction Monitoring Mass Spectrometry: Insights from Quantitation of Activated Kinases

par Urisman, Anatoly, Levin, Rebecca S., Gordan, John D., Webber, James T., Hernandez, Hilda, Ishihama, Yasushi, Shokat, Kevan M., Burlingame, Alma L.
Publié dans Mol Cell Proteomics (2017)

ADAP–SLP-76 Binding Differentially Regulates Supramolecular Activation Cluster (SMAC) Formation Relative to T Cell–APC Conjugation

par Wang, Hongyan, McCann, Fiona E., Gordan, John D., Wu, Xiang, Raab, Monika, Malik, Talat H., Davis, Daniel M., Rudd, Christopher E.
Publié 2004

Integrative genomic analyses of sporadic clear cell Renal Cell Carcinoma define disease subtypes and potential new therapeutic targets

par Dondeti, Vijay R., Wubbenhorst, Bradley, Lal, Priti, Gordan, John D., D'Andrea, Kurt, Attiyeh, Edward F., Simon, M. Celeste, Nathanson, Katherine L.
Publié 2011

The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

par Lum, Julian J., Bui, Thi, Gruber, Michaela, Gordan, John D., DeBerardinis, Ralph J., Covello, Kelly L., Simon, M. Celeste, Thompson, Craig B.
Publié 2007

HIF-2α regulates Oct-4: effects of hypoxiaon stem cell function, embryonic development, and tumor growth

par Covello, Kelly L., Kehler, James, Yu, Hongwei, Gordan, John D., Arsham, Andrew M., Hu, Cheng-Jun, Labosky, Patricia A., Simon, M. Celeste, Keith, Brian
Publié 2006

Erratum

par Wang, Hongyan, McCann, Fiona E., Gordan, John D., Wu, Xiang, Moon, Eun-Yi, Raab, Monika, Malik, Talat H., Davis, Daniel M., Rudd, Christopher E.
Publié 2005

HIF2α inhibition promotes p53 pathway activity, tumor cell death, and radiation responses

par Bertout, Jessica A., Majmundar, Amar J., Gordan, John D., Lam, Jennifer C., Ditsworth, Dara, Keith, Brian, Brown, Eric J., Nathanson, Katherine L., Simon, M. Celeste
Publié 2009

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

par Wang, Jingxiao, Dong, Mingjie, Xu, Zhong, Song, Xinhua, Zhang, Shanshan, Qiao, Yu, Che, Li, Gordan, John, Hu, Kaiwen, Liu, Yan, Calvisi, Diego F., Chen, Xin
Publié dans Oncogene (2018)

Hybrid Capture‐Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1‐Mutant Cholangiocarcinoma Harboring a Novel YWHAZ‐BRAF Fusion...

par Lim, Huat C., Montesion, Meagan, Botton, Thomas, Collisson, Eric A., Umetsu, Sarah E., Behr, Spencer C., Gordan, John D., Stephens, Phil J., Kelley, Robin K.
Publié dans Oncologist (2018)

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

par Evason, Kimberley J., Francisco, Macrina T., Juric, Vladislava, Balakrishnan, Sanjeev, Lopez Pazmino, Maria del Pilar, Gordan, John D., Kakar, Sanjay, Spitsbergen, Jan, Goga, Andrei, Stainier, Didier Y. R.
Publié dans PLoS Genet (2015)

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer

par Donnella, Hayley J, Webber, James T, Levin, Rebecca S, Camarda, Roman, Momcilovic, Olga, Bayani, Nora, Shah, Khyati N, Korkola, James, Shokat, Kevan M, Goga, Andrei, Gordan, John D, Bandyopadhyay, Sourav
Publié dans Nat Chem Biol (2018)

Oncogene Mimicry as a Mechanism of Primary Resistance to BRAF Inhibitors

par Sos, Martin L., Levin, Rebecca S., Gordan, John D., Oses-Prieto, Juan A., Webber, James T., Salt, Megan, Hann, Byron, Burlingame, Alma L., McCormick, Frank, Bandyopadhyay, Sourav, Shokat, Kevan M.
Publié dans Cell Rep (2014)