Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism

Although it is advantageous for hypoxic cells to inhibit protein synthesis and conserve energy, it is also important to translate mRNAs critical for adaptive responses to hypoxic stress. Because internal ribosome entry sites (IRES) have been postulated to mediate this preferential synthesis, we anal...

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Detalhes bibliográficos
Main Authors: Young, Regina M., Wang, Shang-Jui, Gordan, John D., Ji, Xinjun, Liebhaber, Stephen A., Simon, M. Celeste
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423241/
https://ncbi.nlm.nih.gov/pubmed/18430730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710079200
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