Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism

Although it is advantageous for hypoxic cells to inhibit protein synthesis and conserve energy, it is also important to translate mRNAs critical for adaptive responses to hypoxic stress. Because internal ribosome entry sites (IRES) have been postulated to mediate this preferential synthesis, we anal...

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Bibliografiske detaljer
Main Authors: Young, Regina M., Wang, Shang-Jui, Gordan, John D., Ji, Xinjun, Liebhaber, Stephen A., Simon, M. Celeste
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Protein Synthesis, Post-Translational Modification, and Degradation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423241/
https://ncbi.nlm.nih.gov/pubmed/18430730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710079200
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