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Recruitment of the 40S Ribosome Subunit to the 3′-Untranslated Region (UTR) of a Viral mRNA, via the eIF4 Complex, Facilitates Cap-independent Translation

Barley yellow dwarf virus mRNA, which lacks both cap and poly(A) tail, has a translation element (3′-BTE) in its 3′-UTR essential for efficient translation initiation at the 5′-proximal AUG. This mechanism requires eukaryotic initiation factor 4G (eIF4G), subunit of heterodimer eIF4F (plant eIF4F la...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sharma, Sohani Das, Kraft, Jelena J., Miller, W. Allen, Goss, Dixie J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416834/
https://ncbi.nlm.nih.gov/pubmed/25792742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645002
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