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Hypoxia Inducible Factors: Central Regulators of the Tumor Phenotype
Low oxygen levels are a defining characteristic of solid tumors, and responses to hypoxia contribute substantially to the malignant phenotype. Hypoxia-induced gene transcription promotes characteristic tumor behaviors including angiogenesis, invasion, metastasis, de-differentiation and enhanced glyc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215290/ https://ncbi.nlm.nih.gov/pubmed/17208433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2006.12.006 |
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