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Hypoxia inducible factors regulate filaggrin expression and epidermal barrier function

A functional epidermal skin barrier requires the formation of a cornified envelope from terminally differentiating keratinocytes. During this process, multiple genetic and environmental signals coordinately regulate protein expression and tissue differentiation. Here we describe a critical role for...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Wong, Waihay J., Richardson, Theresa, Seykora, John T., Cotsarelis, George, Simon, M. Celeste
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286527/
https://ncbi.nlm.nih.gov/pubmed/24999590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.283
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