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Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypes
Intra-tumoral hypoxia (low oxygen [O(2)] level) is an independent indicator of unfavorable patient diagnosis, and increasing evidence demonstrates that hypoxia contributes to a more aggressive tumor phenotype. Adaptation to hypoxia is predominantly regulated by two structurally related hypoxia induc...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146034/ https://ncbi.nlm.nih.gov/pubmed/19167211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2008.12.001 |
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