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Biology of Hypoxia-Inducible Factor-2α in Development and Disease

The transcriptional response to hypoxia is primarily mediated by two hypoxia-inducible factors – HIF-1α and HIF-2α. While these proteins are highly homologous, increasing evidence suggests they have unique transcriptional targets and differential impact on tumor growth. Furthermore, non-transcriptio...

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Bibliografske podrobnosti
Main Authors: Patel, Shetal A., Simon, M. Celeste
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882207/
https://ncbi.nlm.nih.gov/pubmed/18259197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.17
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