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Biology of Hypoxia-Inducible Factor-2α in Development and Disease
The transcriptional response to hypoxia is primarily mediated by two hypoxia-inducible factors – HIF-1α and HIF-2α. While these proteins are highly homologous, increasing evidence suggests they have unique transcriptional targets and differential impact on tumor growth. Furthermore, non-transcriptio...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882207/ https://ncbi.nlm.nih.gov/pubmed/18259197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.17 |
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