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Biology of Hypoxia-Inducible Factor-2α in Development and Disease

The transcriptional response to hypoxia is primarily mediated by two hypoxia-inducible factors – HIF-1α and HIF-2α. While these proteins are highly homologous, increasing evidence suggests they have unique transcriptional targets and differential impact on tumor growth. Furthermore, non-transcriptio...

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Hlavní autoři: Patel, Shetal A., Simon, M. Celeste
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882207/
https://ncbi.nlm.nih.gov/pubmed/18259197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.17
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