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Hypoxia Inducible Factors, stem cells and cancer
Severely hypoxic regions in tumors result from a combination of rapid cell division and aberrant angiogenesis. The Hypoxia Inducible Factors (HIFs) mediate transcriptional responses to localized hypoxia in normal tissues and in cancers, and can promote tumor progression by altering cellular metaboli...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150586/ https://ncbi.nlm.nih.gov/pubmed/17482542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.04.019 |
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