Hypoxia inducible factors in cancer stem cells

Oxygen is an essential regulator of cellular metabolism, survival, and proliferation. Cellular responses to oxygen levels are monitored, in part, by the transcriptional activity of the hypoxia inducible factors (HIFs). Under hypoxia, HIFs regulate a variety of pro-angiogenic and pro-glycolysis pathw...

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Autors principals: Heddleston, J M, Li, Z, Lathia, J D, Bao, S, Hjelmeland, A B, Rich, J N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833246/
https://ncbi.nlm.nih.gov/pubmed/20104230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605551
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