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Hypoxia inducible factors in cancer stem cells

Oxygen is an essential regulator of cellular metabolism, survival, and proliferation. Cellular responses to oxygen levels are monitored, in part, by the transcriptional activity of the hypoxia inducible factors (HIFs). Under hypoxia, HIFs regulate a variety of pro-angiogenic and pro-glycolysis pathw...

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Detalhes bibliográficos
Main Authors: Heddleston, J M, Li, Z, Lathia, J D, Bao, S, Hjelmeland, A B, Rich, J N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833246/
https://ncbi.nlm.nih.gov/pubmed/20104230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605551
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